Scientist II/Sr. Scientist I, Immunology

Salary Band: $150,000-$200,000

Location: South San Francisco, CA

Job Summary

We are seeking an immunologist with experience in autoimmune and inflammatory diseases (not I/O) who owns the biology. As a member of a highly integrated team of biologists, computational scientists and protein scientists, you will design, execute, and interpret the in vitro and ex vivo experiments that determine whether a target is tractable, whether a compound engages it in human cells, and whether that engagement produces the biology we intended.

You will work in project teams and tackle the questions that determine program progression: is the cellular phenotype on-target, does the mechanism hold up in disease-relevant human systems, and what do the assay data tell us about whether to advance a series. Our research is focused on small-molecule modulation of immune signaling pathways that drive pathogenic inflammation, with the aim of achieving the selectivity and durability that current…