Scientist III - Flow Cytometry Services

Performing critical work that impacts our industry and our world’s health while problem solving and innovating in the field – that is what Scientists at KCAS Bio get to do every day. If that gets you excited too, then maybe working as a Scientist at KCAS Bio is the role for you.

When you work as a Scientist III in the Flow Cytometry group at KCAS, you get to further our mission by applying your knowledge in bioanalytical and scientific principles to independently execute studies and support the development, qualification, and validation of flow cytometry and cell-based assays. You will utilize your strong scientific foundation to assess assay performance, interpret data, troubleshoot complex technical issues, and ensure the integrity and quality of study results. Our Flow Cytometry team utilizes advanced instrumentation and analytical techniques to support bioanalytical testing in drug discovery, preclinical, and clinical studies, including immunophenotyping, cell-based assays, and biomarker analysis in biological matrices.

In this role, we will rely on you to:

Independently execute and support flow cytometry studies from study setup through data generation, analysis, and reporting

Develop, optimize, qualify, validate, and transfer flow cytometry methods in support of preclinical and clinical studies

Design and optimize multiparametric flow cytometry panels, including selection and evaluation of antibody clones, fluorochromes, titrations, controls, sample matrices, and gating strategies

Perform flow cytometry sample preparation, staining, data acquisition, analysis, and interpretation

Operate conventional and spectral flow cytometry instrumentation, including platforms such as Cytek Aurora and BD flow cytometers

Develop and optimize assays utilizing biological matrices such as whole blood, fresh or cryopreserved PBMCs, bone marrow, tissue, and cell lines

Analyze and interpret complex flow cytometry data and prepare data summaries and presentations for internal and client reviews

Evaluate assay performance characteristics including precision, accuracy, sensitivity, selectivity, stability, robustness, linearity, and other applicable parameters

Troubleshoot complex assay, sample, reagent, instrumentation, and data analysis issues and develop scientifically sound solutions

Apply knowledge of immunology and cell biology to immunophenotyping, biomarker, and functional cellular assay applications

Support study activities involving applications such as immune profiling, receptor occupancy, target engagement, intracellular marker analysis, proliferation, and other functional cellular endpoints as applicable

Ensure proper sample identification, handling, processing, storage, and tracking throughout study execution

Maintain accurate and complete documentation in accordance with study protocols, SOPs, and applicable regulatory and quality requirements

Review and interpret scientific data to identify trends, inconsistencies, and potential risks to study execution or data quality

Prepare and review protocols, study documentation, data summaries, and reports

Communicate scientific findings, study progress, technical challenges, and recommendations to project teams, management, and clients as appropriate

Provide technical guidance and training to less experienced scientific staff

Collaborate with Quality Assurance and other cross-functional teams to resolve study or data-related issues

Maintain knowledge of current scientific, technological, and regulatory developments relevant to flow cytometry

Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values

To qualify specifically for this role, you will have:

Bachelor’s degree in Biology, Immunology, Cell Biology, or related scientific field

At least 4 years of relevant laboratory experience in flow cytometry, immunology, cell biology, bioanalysis, or a related area

Strong hands-on experience with flow cytometry techniques and instrumentation

Experience with spectral and/or conventional flow cytometry

Experience with multiparametric flow cytometry, including panel design and optimization, staining, controls, data acquisition, gating strategies, and data interpretation

Experience developing, optimizing, qualifying, validating, and/or transferring flow cytometry methods

Experience working with biological matrices such as whole blood and PBMCs

Strong understanding of immunology, cell biology, immunophenotyping, and cell-based assay principles

Experience troubleshooting complex flow cytometry assays, reagents, instrumentation, and data quality issues

Experience with flow cytometry data analysis software

Strong understanding of assay performance characteristics and fit-for-purpose method development and validation

Experience working within SOP-driven and regulated laboratory environments

Strong technical documentation skills with a commitment to data integrity and scientific quality

Strong written and verbal communication skills with the ability to communicate scientific information effectively

Ability to work independently while collaborating effectively with scientific and cross-functional teams

Ability to provide technical guidance and training to less experienced scientists

Depending on your background and qualifications, we may consider hiring you for one of three levels of Scientist roles at KCAS Bio. This will be determined during the interview process.

(Please note this is a representative summary of responsibilities, not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)

WHO YOU ARE You will thrive at KCAS Bio if you enjoy a relational environment, are purpose- and values-driven, embrace constant development and supportive leadership, and enjoy being part of innovative work.

WHAT YOU’LL GET Our benefits include, and extend beyond, the traditional package. At KCAS Bio, you will enjoy company sponsored events like food trucks, family days and spirit days. You will grow in your career with KCAS University. You will be able to connect with like-minded employees to further KCAS Bio's approach to key areas such as wellness, inclusion, and community outreach. You will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.

Learn more about the Benefits at KCAS Bio

WHO WE ARE We are a fast-growing contract research organization (CRO) headquartered in Kansas City, pioneering the latest drug development in both human and animal health fields. Demand for our expertise is growing and so is our need for great people to work in nimble, empowered teams committed to one another’s growth. At KCAS Bio, we advance both great science AND great people.

Learn more about what it is like to work at KCAS Bio

KCAS Bio is proud to be an Equal Opportunity Employer. Among other things, we provide equal employment opportunities without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity, or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs, observances, and practices. Anyone who needs reasonable accommodation may send an email to kcasrecruiting@kcasbio.com or call 913-248-3000 (for TTY assistance call 711) and ask for Human Resources.

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