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Systems Engineer II

Ultima Genomics

Fremont, CA · Posted September 28, 2026

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This listing does not state pay. Across 40 open systems engineer ii listings that state pay, the middle half runs $100,000 to $110,000 and the median is $100,000.

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About the job

Rapidly Growing Life Sciences Technology Company

Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.

We are looking for a highly motivated Systems Engineer II to join our team!

As a Systems Engineer II, you will contribute to the development, testing, and optimization of cutting-edge instrumentation as part of our systems engineering team.

This is a full time onsite position at our Fremont, CA location.

How You’ll Contribute

Execute end-to-end development including planning, development, optimization, and testing of workflows for life science automation and liquid handling systems. Own workflow from concept to customer delivery

Collaborate with hardware and software development engineers to implement improvements in automation process efficiency and reliability

Operate, troubleshoot and customize hardware and software components

Interface with stakeholders to collect and define requirements, and provide user training and documentation

Work with Chemistry and Biology teams to translate and optimize manual lab processes on automated machines

Other job duties as assigned

Qualifications, Skills, Knowledge & Abilities

BS or MS in Biomedical Engineering, Mechanical Engineering, Physics, Biology, Chemistry or closely related field

2+ years of relevant experience

Experience in the development of scientific instruments from a systems integration perspective is strongly preferred

Basic understanding of molecular biology, genomics, and other standard life science lab workflows and equipment

Familiarity with a scripting language such as Python

Meticulous and detail oriented with a hands-on approach to work

Ability to define and follow complex operating procedures

Excellent organizational, communication and presentation skills

#LI-Onsite

At Ultima Genomics, your base pay is one part of your total compensation package. This role pays between $100,000 and $120,000, if performed in California, and your actual base pay will depend on your skills, qualifications, experience, and location. Please note that the compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits. This role is also eligible for a competitive benefits package that includes: medical, dental, vision, life, and disability insurance; 401(k) retirement plan; flexible spending & health savings account; paid holidays; paid time off; employee assistance program; and other company benefits.

Ultima Genomics is proud to be an equal opportunity workplace and is an affirmative action employer. We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws. See also Ultima Genomics’ EEO Policy and Know Your Rights . If you have a disability or special need that requires accommodation, please let us know by contacting recruiting@ultimagen.com .