Application Architect

Medpace Holdings

Cincinnati, OH · Posted September 8, 2026

More in Ohio job market · Pharmaceuticals & Biotech · Engineering jobs

About the job

Our organization’s systems are evolving rapidly to leverage the latest technologies as we continue to exceed the needs of our customers, and we are currently seeking a full-time Application Architect to join our team. The Application Architect will collaborate closely with development teams and subject matter experts to design solutions for enhancements, integrations, migrations, and other system needs. Additionally, the Application Architect will research new technologies, including the building of prototypes, to identify and prove business value in applying new technologies to our systems. A strong aptitude for designing detailed solutions for systems and a passion for technology are essential for this role. An exciting career of growth and development awaits the Application Architect that joins our team.

Responsibilities

Oversee the design process for application software;

Implement and recommend viable architectural approaches that support long-term maintainability, extensibility, and interoperability of enterprise applications;

Identify and evaluate potential risks in systems in relation to data integrity, security, and disaster recovery;

Provide clear guidance to software development teams regarding software development patterns and proactively monitor the adherence to accepted patterns;

Contribute to the shared private code repositories after aggregating feedback from the software development teams;

Maintain a versioning and governance approach to private code repositories, and ensure that applications are leveraging this code as appropriate;

Build and test prototypes;

Liaise with software development teams to craft and automate deployments;

Conduct code reviews, security reviews, and architectural reviews, and provide solutions/improvements as necessary;

Complete other projects and responsibilities as assigned.

Qualifications

Bachelor’s Degree or higher in Computer Science or closely related;

8+ years of experience in Software Development;

Experience with a cloud-based platform (Azure) is a plus;

Experience with microservices and event-driven architectures;

Expert knowledge of APIs, Databases, and server-side language (e.g. C#);

Expert understanding of Front-End Frameworks (e.g. Angular);

Demonstrated ability to learn new technologies, systems and processes;

Excellent analytical, written, and oral communication skills.

#LI-Hybrid

Medpace Overview

Medpace is a full-service clinical contract research organization (CRO) providing phase l-lV clinical development services to the biotechnology, pharmaceutical, and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics through the advancement of clinical research. We leverage in-country regulatory and therapeutic expertise across all major therapeutic areas including oncology, cardiology, metabolic, endocrinology, central nervous system, and anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, we employ more than 6,500 people across 40+ countries.

Why Medpace?

When you join Medpace, you become part of an innovative team that brings cutting-edge therapies to market while building a meaningful and rewarding career focused on scientific excellence and improving patient outcomes around the world through continuous learning and cross-functional collaboration.

Purpose-Driven Work

Work alongside physicians, scientists, and industry-leading experts committed to advancing the global development of medical therapeutics through clinical research excellence

Collaborative Culture

Contribute to an interactive team environment that empowers decision making, creative thinking, and continuous learning through open communication and mutual trust.

Leadership throughout Medpace is both accessible and approachable

Continuous Growth & Development

Office based environment with on-site mentors

Defined career paths with clear advancement opportunities

Industry renowned onboarding and training programs designed to accelerate professional development

Ongoing training and continuous learning opportunities throughout your career

An environment that encourages employees to influence change, contribute ideas, and grow quickly

Other Employee Benefits

Competitive compensation programs that recognize and reward performance

Comprehensive health, wellness, retirement, and PTO benefits

Office based culture with occasional WFH that provides flexibility for eligible positions after training

Company-sponsored social events and intramural sports

Cincinnati Headquarters Experience

A modern corporate campus designed to support collaboration and productivity

Multiple on-site dining options in the heart of Madison Square

Free on-site parking

Convenient access to on-site 24-7 fitness and wellness facilities

What to Expect Next

A Medpace team member will review your application and if your profile matches our current needs, you will be contacted for an interview. While we review all applications carefully, we are unable to respond to every applicant, and only candidates selected for interviews will be contacted.