Senior Software Engineer, Backend
Pathai
Boston, MA · Posted September 11, 2026
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Where Boston, MA ranks
Where Boston, MA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #1Best cities for life sciences and biotech jobs793 openings · of 41
- #1Cities with the most jobs that do not need a four-year degree in New England390 jobs · of 14
- #1Best cities for AI-skill jobs in New England21% · of 28
- #1Best cities for software and engineering jobs in New England910 openings · of 24
- #1Best all-round cities for mid-career professionals in the Northeast71 / 100 · of 26
- #1Best all-round cities for mid-career professionals in New England71 / 100 · of 11
Rankings about engineering jobs
- Best cities for software and engineering jobs #1 San Francisco (3,412 openings)
- Best cities for engineering pay after cost of living #1 San Mateo ($216k)
- Most requested AI skills in engineering jobs #1 AI tools in daily work (6.1%)
- AI tools named most often in engineering jobs #1 Claude (1.7%)
- Employers with the most engineering jobs #1 Amazon (2,992 roles)
Pay compared with the market
This listing does not state pay. Across 1,355 open senior software engineer listings that state pay, the middle half runs $162,500 to $222,000 and the median is $195,000.
Listed pay is what employers advertise, not what people are paid.
Senior Software Engineer salaries by state · Check your own pay
How AI is used in this kind of work
Among software developers, AI is already used for some of the tasks. Measured exposure for software developers: 29% (some).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
Skills this job asks for
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About the job
PathAI's mission is to improve patient outcomes with AI-powered pathology.
Our platform promises substantial improvements to the accuracy of diagnosis and the efficacy of treatment of diseases like cancer, leveraging modern approaches in machine learning and artificial intelligence. We have a track record of success in deploying AI algorithms for histopathology in translational research, pathology labs and clinical trials. Rigorous science and careful analysis is critical to the success of everything we do. Our team, composed of diverse employees with a wide range of backgrounds and experiences, is passionate about solving challenging problems and making a huge impact on patient outcomes.
At PathAI, we are constantly evaluating our tech stack and our current tools consist of:
Languages & Frameworks : Python, JavaScript, Django / DRF, FastAPI, Vue
Platform : EKS (Kubernetes), S3, RDS / PostgreSQL, SQS, MSK (Kafka)
Tooling : GitLab CI/CD, Terraform, Docker, Datadog
The Opportunity
We’re looking for a backend focused Senior Software Engineer to join our Integrations team. You will design, build, and maintain critical APIs and data pipelines that enable seamless clinical workflows and real-time data exchange across external systems and our core product.
You will drive the architecture of our application platform, considering the team and our future product roadmap.
You will collaborate with product, design, machine learning, and infrastructure teams.
You will drive and uphold high engineering standards, bringing consistency to the codebases you encounter and ensuring software is adequately reviewed, tested, and integrated.
You will foster a culture of continuous learning by mentoring teammates and sharing technical knowledge.
You will champion code quality for both your individual contributions and the broader team's output.
You will contribute to a SaaS platform used ensuring reliability, data integrity, and compliance with industry standards.
You will collaborate with clinical, QA, and regulatory teams to ensure software changes meet validation expectations and support inspection readiness.
Who You Are: (Required)
You have a BS in Computer Science, Software Engineering or closely related technical field.
You have 5+ years of full life cycle development experience.
You have demonstrated the ability to take on complex tasks, learn quickly and work in a proactive manner.
You have demonstrated experience and skills in designing and building Python-based (FastAPI or Django) applications.
You have a demonstrated foundation in data structures, algorithms, and OO design.
You have a demonstrated ability to collaborate with a distributed team and to work autonomously on projects; You have demonstrated problem-solving skills and the ability to work in a fast-paced, agile environment.
You have strong interpersonal and communication skills, with the ability to attend client-facing meetings and explain technical concepts to non-experts.
You have demonstrated cloud platform experience (AWS)
Preferred:
You have an advanced degree in Computer Science, Software Engineering or closely related technical field
You have experience working in the healthtech industry, including working with HL7, HL7 FHIR, or DICOM
You have experience with modern frontend JavaScript frameworks such as React, Vue, or equivalent for building responsive, user-friendly interfaces.
You have hands-on experience with CI/CD tools, e.g. GitLab CI
You have demonstrated knowledge of containerization technologies like Docker and container orchestration tools like Kubernetes
You have knowledge of some IaC framework
You have experience deploying and monitoring VPNs
You have excellent organizational skills and the ability to prioritize and manage multiple projects efficiently.
This is a hybrid position based in Boston, MA. Relocation benefits are not available for this position.
The expected salary range for this position based on the primary location Boston, MA is $127,500 - $195,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.
PathAI is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.