AI and Agentic Engineer II
Exelixis
Alameda, CA · Posted November 9, 2026
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Where Alameda, CA ranks
Where Alameda, CA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #2Best cities for aerospace and defense pay after cost of living$167k · of 19
- #3Best cities for director and executive jobs in the West Coast27% · of 71
- #6Cities that post pay most often47% · of 100
- #9Best cities for pay after cost of living in California$176k · of 32
- #11Best cities for pay after cost of living in the West Coast$176k · of 39
- #14Best cities for pay after cost of living$176k · of 100
Rankings about data & analytics jobs
- Best cities for data and analytics jobs #1 New York (1,713 openings)
- Best cities for data and analytics pay after cost of living #1 Foster ($232k)
- Most requested AI skills in data and analytics jobs #1 Machine learning engineering (17.1%)
- AI tools named most often in data and analytics jobs #1 Databricks (7.6%)
- Employers with the most data and analytics jobs #1 Amazon (711 roles)
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How AI is used in this kind of work
Among computer and information research scientists, AI is already used for a large share of the tasks. Measured exposure for computer and information research scientists: 34% (high).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
Skills this job asks for
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About the job
SUMMARY/JOB PURPOSE
The Engineer II - AI and Agentic is responsible for designing, building, and deploying production-grade agentic applications that automate multi-step IT and business workflows across Exelixis. This role delivers spec-driven, testable, and secure AI solutions, contributes to platform patterns and reusable components, while advancing the engineering standards.
ESSENTIAL DUTIES/RESPONSIBILITIES
• Design and deliver end-to-end agentic applications and multi-agent workflows that automate IT and business processes.
• Convert prototypes into hardened, production-ready services with clear specifications, modular design, robust error handling, and comprehensive test coverage.
• Integrate LLMs, prompts, tools, APIs, and enterprise data sources (e.g., Bedrock, Databricks Mosaic AI, MCP servers) into reliable use cases.
• Implement CI/CD pipelines, automated evaluation harnesses, observability, and artifact versioning for AI/agent workloads.
• Author architecture notes, runbooks, SOPs, and technical documentation to support adoption, operability, and maintainability.
• Lead prompt/spec reviews, code reviews, threat modeling exercises, and release-readiness gates.
• Apply and evangelize secure-by-design and responsible AI principles, including data governance, privacy, and safe prompting aligned to organizational policy
• Contribute reusable components, patterns, and internal libraries to the platform
• Partner with product managers, security, and platform teams to translate business needs into scalable technical solutions
• Performs other duties as assigned
• Complies with all policies and standards
SUPERVISORY RESPONSIBILITIES
• No supervisory responsibilities
EDUCATION/EXPERIENCE/KNOWLEDGE/SKILLS & ABILITIES
Education
• Bachelor's degree in Computer Science, Artificial Intelligence, Data Science, Software Engineering, or a related field and 5 years of related experience; or
• Master’s degree in Computer Science, Artificial Intelligence, Data Science, Software Engineering, or a related field and 3 year or related experience; or
• Equivalent combination of education and experience.
Experience
• 2 - 4 years of relevant experience in AI application, data science, automation, or related technical work, including hands-on experience building or contributing to LLM-enabled applications, agentic workflows, API integrations,
Knowledge, Skills and Abilities
Required:
• Intermediate to Advanced proficiency in Python and/or JavaScript/TypeScript, including modular design, testing, and packaging.
• Intermediate proficiency with agent frameworks and agentic patterns: tool use, planning/execution loops, guardrails, evaluation, and prompt/version management.
• Intermediate proficiency building and consuming REST APIs, and integrating enterprise systems with OAuth/JWT, secrets management, and secure data handling.
• Intermediate proficiency with CI/CD, automated testing (unit/integration), linting, and observability for AI applications.
• Intermediate understanding of security best practices, architecture design principles, and responsible AI/data governance.
• Intermediate communication skills, written and verbal, and demonstrated ability to collaborate with cross-functional stakeholders and mentor junior engineers.
• Intermediate experience with cloud AI platforms — preferably AWS Cloud, AWS Bedrock, and Databricks Mosaic AI — and vector stores or retrieval-augmented generation (RAG) patterns.
• Intermediate knowledge of AI-native engineering using Claude Code, Codex, GitHub Copilot, or equivalent coding agents.
Preferred:
• Experience delivering evaluation frameworks, red-teaming, or LLM observability tooling.
Travel Requirements
• No travel is required for this position.
#LI-EZ1
Location: Alameda, CA

Range for this position: $170,000 - $215,000

The base pay offered will take into account job-related knowledge, skills, experience and internal equity, among other factors.
In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.
Exelixis is an Equal Opportunity Employer. We are committed to fostering an inclusive environment where everyone can thrive. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, pregnancy (including lactation, childbirth, or related medical conditions), sexual orientation, gender identity, age (40 and over), national origin or ancestry, citizenship or immigration status, physical or mental disability, genetic information (including testing and characteristics), veteran status, uniformed servicemember status, or any other characteristic protected by applicable federal, state, or local law. We are also committed to providing reasonable accommodations to qualified individuals with disabilities, unless undue hardship and/or a direct threat to the health and/or safety of the individual or others would result.
If you have a disability and need an accommodation in relation to the recruiting process, please email us at: ApplicantAccommodations@exelixis.com.
Exelixis is an E-Verify employer.
WORKING CONDITIONS:
Our office is a modern space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.
DISCLAIMER: The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.