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Sr. Director, Infrastructure & Operations

Scholar Rock Holding

Cambridge, MA · $245k–$325k a year · Posted October 5, 2026

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This listing pays about $285,000 a year. Across 32 open sr director listings that state pay, the middle half runs $217,000 to $289,500 and the median is $240,500. That is inside the middle half of those listings, 19% above the median.

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About the job

Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need. As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at ScholarRock.com and follow @ScholarRock on X and on LinkedIn.

Summary of Position:

Scholar Rock is seeking a Senior Director, Infrastructure & IT Operations to lead and scale the technology infrastructure and IT operations supporting our growing global organization.

Scholar Rock is looking for a leader who is equally comfortable building the roadmap and rolling up their sleeves to deliver it. This individual brings strong technical judgment, a high sense of ownership, and a service mindset and knows how to build an IT organization that is scalable as the company grows.

This is a hands-on leadership role responsible for the reliability, scalability, and day-to-day operation of Scholar Rock’s IT environment across the U.S. and international locations. The successful candidate will set direction, build and develop the team, and remain close enough to the technology and business to solve problems and drive execution.

This leader will strengthen the capabilities we need today while building the infrastructure and operating model required to support Scholar Rock’s continued growth and global commercialization.

Position Responsibilities

Own Scholar Rock’s global IT infrastructure and operations, including cloud and Microsoft platforms, networks, identity, endpoints, collaboration technologies, and end-user computing

Lead IT service delivery and end-user support, ensuring responsive, reliable support and a strong employee technology experience

Build scalable infrastructure, operating processes, and standards to support continued growth and an expanding global footprint

Drive operational excellence and reliability, including incident and problem management, root-cause resolution, monitoring, technology lifecycle management, capacity planning, and continuous improvement

Ensure appropriate business continuity, disaster recovery, backup, and infrastructure resilience capabilities are established, tested, and maintained

Lead technology infrastructure and operational readiness for new offices and international expansion

Build and develop a high-performing team with strong technical capability, clear accountability, documented processes, and appropriate coverage and redundancy across critical services

Own managed service providers and key technology vendors, establishing clear performance expectations, service levels, cost and accountability

Partner across IT and the business to ensure infrastructure and operations meet security, compliance, and business requirements

Serve as a trusted technology partner to the business while remaining hands-on and engaged in execution, particularly for complex issues and critical incidents

Own the Infrastructure & IT Operations budget, including technology investments, licensing, managed services, and vendor contracts, balancing service, scalability, and cost

Ensure infrastructure and operational practices support applicable GxP, SOX, security, privacy, and audit-readiness requirements, in partnership with Quality, Security, and Compliance

Candidate Qualifications

Bachelor’s degree in information technology, Computer Science, Engineering, or related discipline

12+ years of progressive IT experience with leadership responsibility across infrastructure and IT operations/service delivery

Strong technical knowledge across Microsoft 365/Azure, identity and access, endpoint management, networking, cloud technologies, and enterprise IT operations

Demonstrated experience building and scaling IT capabilities, teams, and operating models in a growing organization

Experience supporting a geographically distributed or global organization

Proven ability to lead internal teams and external service providers while maintaining clear internal ownership and accountability

Strong operational judgment with a willingness to engage directly when needed

Biotechnology, pharmaceutical, life sciences, or other regulated-industry experience preferred

Scholar Rock is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.