Executive Medical Director, Oncology

BACK TO JOBS Executive Medical Director, Oncology APPLY NOW Executive Medical Director, Oncology Company: High-Growth Clinical-Stage Oncology Biotechnology Company Location: San Diego, CA | Hybrid Employment Type: Permanent The Opportunity Brio Resource Group is partnering with a high-growth clinical-stage oncology biotechnology company to identify an Executive Medical Director, Oncology . This senior medical leadership position will guide oncology development programs and translate emerging clinical data into actionable program decisions. The successful candidate will shape clinical strategy, study design, medical oversight, and engagement with investigators and scientific experts as the company advances its oncology portfolio through important development milestones. Key Responsibilities Define and lead clinical-development strategies across assigned oncology programs. Provide medical and scientific leadership from protocol development through study execution, data analysis, and reporting. Design and review clinical protocols, endpoints, eligibility criteria, treatment plans, and development pathways. Oversee medical monitoring and provide guidance on patient safety, eligibility, protocol deviations, and emerging clinical issues. Evaluate safety, efficacy, pharmacodynamic, biomarker, and other clinical data to inform program decisions. Translate clinical findings into recommendations regarding dose, schedule, patient selection, combination strategies, and future studies. Contribute medical content to clinical-development plans, investigator brochures, regulatory submissions, briefing documents, and clinical study reports. Partner closely with Clinical Operations, Regulatory Affairs, Pharmacovigilance, Biometrics, Translational Medicine, and CMC. Support interactions with the FDA and other global health authorities. Establish relationships with investigators, key opinion leaders, advisory boards, and external scientific experts. Present clinical strategy, data, risks, and recommendations to executive leadership, governance committees, and external stakeholders. Support clinical due diligence, partnering activities, publications, and scientific presentations. Qualifications MD or DO degree with significant oncology clinical and drug-development experience. Board certification or eligibility in medical oncology, hematology/oncology, or another relevant specialty is strongly preferred. Demonstrated experience providing medical leadership for early- and/or late-stage oncology clinical trials. Strong knowledge of oncology study design, endpoints, medical monitoring, safety assessment, and benefit-risk evaluation. Experience interpreting complex clinical, biomarker, pharmacology, and translational data. Experience preparing clinical and medical content for regulatory submissions and health-authority interactions. Established relationships with oncology investigators, key opinion leaders, and scientific experts. Ability to lead effectively across Clinical Operations, Regulatory Affairs, Safety, Biometrics, and Translational Medicine. Strong executive communication, scientific presentation, decision-making, and influencing skills. Ability to operate strategically and hands-on within a fast-moving clinical-stage biotechnology environment. Why Consider This Opportunity? This role offers the opportunity to provide medical leadership for innovative oncology programs, influence critical development and portfolio decisions, and work closely with accomplished scientists, investigators, and company leaders advancing potential new treatments for patients with cancer. A complete job description, compensation information, benefits, and additional company details will be provided following an initial résumé review.