Director, Global Compensation - Commercial
Alnylam Pharmaceuticals
Cambridge, MA · $202k–$273k a day · Posted September 14, 2026
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About the job
Overview
We are seeking a Director, Global Compensation, to serve as the lead compensation partner for Alnylam’s Global Commercial organization. This individual will provide strategic compensation expertise across base pay, market competitiveness, job architecture, sales incentive compensation, equity compensation, and broader total rewards programs to support a growing commercial business. Reporting to the Senior Director, Global Compensation, this role will partner closely with Commercial leaders, HR Business Partners, Commercial Business Operations, and other key stakeholders to design, evaluate, and evolve compensation programs that support talent attraction, retention, engagement, and business performance.
Key Responsibilities
Serve as the primary compensation business partner to Alnylam’s Global Commercial organization, partnering closely with Commercial leaders, HR Business Partners, and Finance, providing strategic guidance on compensation programs, pay decisions, talent investments, and market competitiveness, and strategies that support business objectives and organizational growth.
Conduct market analyses, benchmarking, and compensation modeling to support hiring, retention, organizational design, and workforce planning decisions across commercial functions.
Evaluate the effectiveness and competitiveness of compensation and sales incentive programs and recommend enhancements that align employee rewards with business outcomes.
Design, recommend, and implement data driven compensation programs by evaluating market practices, trends, regulatory requirements, analyzing costs, and ensuring Alnylam’s competitive advantage in total rewards.
Provide strategic, consultative thought leadership to the business and HR Business Partners on all compensation matters, including salary management, sales incentive design, total rewards philosophy, programs, policies, job architecture, and creative support of strategic objectives.
Partner closely with Commercial Operations to provide compensation expertise and strategic guidance on sales incentive plan design, performance measures, quota methodologies, payout governance, contests, and incentive effectiveness to ensure programs are competitive, motivating, compliant, and aligned with business objectives.
Support the enhancement and evolution of compensation programs aligned with the company’s current lifecycle stage and educate employees on programs across global locations.
Develop executive-ready analyses, insights, and recommendations to support compensation decisions and leadership review processes.
Lead complex global compensation projects from conception through implementation, including developing project plans, timelines, stakeholder management, governance, communications, and appropriate change management activities.
Identify opportunities for process improvements and implement best practices to support programs.
Qualifications
Seasoned strategic and operational compensation professional and leader with at least 10 years’ of relevant experience, with the ability to critically assess and evolve existing compensation and sales incentive plans, programs, policies, and processes for a growth-oriented biopharmaceutical company (or similar fast-paced environment)
Demonstrated ability to advise, challenge, and influence colleagues and build relationships at all levels of an organization
Demonstrated experience supporting commercial organizations leading the design, evaluation, or strategic consultation of compensation and incentive programs, including sales incentive plans
Strong understanding of commercial compensation practices, including sales incentive compensation principles, pay-for-performance philosophies, incentive governance, quota-based compensation structures, and market competitiveness
Highly analytical, with the ability to evaluate complex data and make informed recommendations.
Experience supporting global compensation programs and partnering with business leaders across multiple geographies preferred
Working knowledge of equity compensation programs and their role within a broader total rewards strategy is preferred
Experience supporting commercial organizations within biotechnology, pharmaceutical, medical device, or related life sciences industries strongly preferred
Excellent written and verbal communication, exceptional attention to detail, and ability to build credibility with senior business leaders and translate complex compensation concepts into clear, actionable recommendations
A team player able to collaborate with partners and stakeholders across HR and outside HR
Advanced proficiency in MS Excel
Willingness to travel occasionally
About Alnylam
We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.
Before applying, please review Alnylam's Candidate Privacy Notice regarding how Alnylam handles Personal Data you provide with your application for employment.
#LI-MH1 #LI-Hybrid
The pay range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
U.S. Pay Range $201,500 — $272,600 USD