Lab Operations Specialist
Calico
South San Francisco, CA · Posted October 13, 2026
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About the job
Who We Are:
Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.
Position Description:
Calico is seeking an exceptional and experienced Lab Operations Specialist who will work within the Facilities and Operations group. The candidate will also work closely with the research groups and scientists and with other functional groups at Calico.
Responsibilities will include:
Personnel management
Train and mentor personnel on the Operations team, including Lab Assistants
Coordinate external Operations contractors and determine resources needed
Lab management, including oversight of shared lab areas and equipment
Lab equipment management
Troubleshoot lab equipment per manufacturer recommendations
Coordinate repairs and preventative maintenance with vendors
Schedule installation of new lab equipment
Assist with purchasing service contracts
Maintain asset tag system of new/existing lab equipment
Coordinate onsite pipette calibrations
Schedule routine incubator decontaminations and freezer defrosts
Assist with lab monitoring notification system for alerts and maintenance, including material transfer of samples in the event of a freezer or cryostorage failure
Lab services management
Coordination of onsite stockrooms (including vendor management)
Routine checking of shared lab areas to ensure equipment and/or lab needs are met via requests from end users
Maintain and improve lab organizational processes
Strategic planning for future needs and processes
Involvement in cross-functional roles within facilities and lab operations department
Intellectual property management
Maintenance of the laboratory notebook processes and systems
Project management
Assist in managing and tracking ongoing and new projects within the Facilities and Operations team and cross-team projects with other functional groups
Position Requirements:
Bachelor's degree in a scientific field (e.g., Biology, Chemistry, Biochemistry) or equivalent
3+ years of experience in Operations in a laboratory environment, prior people/team management preferred
Great communication skills (written and oral) and strong team player
Ability to balance a broad range of organizational needs with appropriate attention to detail and focus on assigned tasks
Ability to handle Operations issues in a fast-paced environment with a customer-focused attitude
Must be willing to work onsite 5 days a week
The estimated base salary range for this role is $105,000 - $115,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.