Research Associate II, Single Cell and Spatial Core

PROGRAM DESCRIPTION The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI's intramural Center for Cancer Research (CCR). The dedicated units provide expertise in electron microscopy, protein characterization, mass spectrometry, protein expression, optical microscopy, and genomics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR), where CRTP scientists work collaboratively with intramural NCI investigators to provide research technologies and expertise. KEY ROLES/RESPONSIBILITIES We are seeking a highly motivated Research Associate to join the Single Cell and Spatial Core (SCSC) of the Center for Cancer Research (CCR) at NCI. The SCSC provides support for state-of-the-art single cell sequencing and spatial profiling technologies to basic and translational cancer research. This Research Associate will have a role in: Supporting single cell sequencing projects, including performing cell counts, generating next generation sequencing libraries, performing sequencing, and assessing resulting data in coordination with other members of the SCSC team. Assisting with general upkeep of the lab, including archiving samples, ordering, and managing stock levels. Collaborating with other members of the SCSC team to support experimental design, sample preparation, and project troubleshooting. Additional tasks may be assigned, and work responsibilities may change as the Single Cell and Spatial Core evolves to support the needs of NCI CCR. This is a laboratory-based position that is onsite on the main NIH Bethesda campus. There may be occasions when you will be expected to work beyond the standard 8-hour day or adjust your work schedule to accommodate the handling of samples later in the day. BASIC QUALIFICATIONS To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below: Possession of Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency. In addition to the education requirement, a minimum of five (5) years of experience performing cell and molecular biology experiments. Familiarity with next generation sequencing methods. Ability to obtain and maintain a security clearance. PREFERRED QUALIFICATIONS Candidates with these desired skills will be given preferential consideration: Demonstrated experience in the area of single cell assays and sequencing. Experience with next generation sequencing (NGS) library preparation, and DNA quantitation. General knowledge and experience with cell biology, including cell culture, cell sorting, viability assessment, and counting. Experience working in a core facility or other team-based environment. Demonstrated ability to rapidly learn new technologies and troubleshoot experiments and assay workflows. Knowledge and background experience in cancer biology and immunology. Excellent written and verbal communication skills. Strong attention to detail and organizational skills, with the ability to manage multiple projects concurrently while maintaining high-quality work. JOB HAZARDS This position is subject to working with or has the potential for exposure to animals(s) and/or animal material(s). This position is subject to working with or has the potential for exposure to infectious material, requiring medical clearance and immunizations.