Senior Statistician II

Senior Statistician II has sufficient experience working as a statistician in the pharmaceutical industry to be working independently on activities relating to design, delivery and interpretation, preclinical studies, regulatory submissions and/or commercialisation. This individual is able to perform and communicate results of more technical analyses, and able to guide less experienced staff. They have the scope to develop creative statistical ideas and approaches, and to apply them in their work. Competent individual contributor with excellent cross-functional collaboration.

The Senior Statistician II may work directly within a project and/or support statistical methodological advances.

The accountabilities for supporting projects directly are:

Provide statistical expertise for complex design and interpretation for preclinical or clinical programmes, high level internal governance committees, regulatory submissions and/or commercialisation

Analyse internal and external information, perform modelling and simulation to inform design decisions and the development of decision criteria

Develop a Statistical Analysis plan for complex studies and/or project deliveries

Act as a coach/guide for less experienced statisticians in the production of analysis, supporting graphics and analysis tables for study reports, Global Medical Affairs studies or publications

Able to analyse, interpret, summarise and communicate results of complex studies

Contribute to the regulatory submissions including specification of overview documents and response to regulatory questions

Identify opportunities for the application of modelling and simulation to improve study design

Identify opportunities to improve the methodology and provide practical solutions for problems

Identify and apply statistical methodology to improve the process and delivery activities

Contribute to the development of best practice to improve quality, efficiency and effectiveness

Accountable for the quality of their statistical work; provide discipline-specific understanding, insight and constructive challenge and take ownership of development needs, seek coaching or training opportunities

The accountabilities for supporting statistical methodological advances are:

Under guidance of a more experienced statistician, produces pragmatic solutions, often within a tight time scale where the emphasis is to deliver first, then refine and develop solutions thereafter.

Draft statistical analysis plans for complex studies

Provide consultancy within area of expertise to fellow statisticians working within therapeutically aligned statistics groups, as well as medical scientists and other key roles across the business

Investigate and apply novel statistical approaches, for relevant statistical issues and/or regulatory guidance and/or value demonstration

Investigate and improve statistical approaches, establish standards and best practice, develop and implement new methodology interacting with external scientists

Identify new areas where we can add value, developing collaborative relationships with the external scientific/academic community and maintaining academic links

Contribute to/or lead the development of a process improvement and/or capability area within the Department

Develop a strong understanding of the pharma business/AZ ways of working

Communicate research and results internally and externally through participation at conferences and journal publications.

Key relationships to reach solutions

All levels of functions within Biometrics

Therapeutic Area scientists

Collaboration partners in other departments

Drug project leading roles in GPT and CPT

Vendor counterparts as well as Project Managers and other Biometrics contacts

Education, Qualifications, Skills and Experience

Master’s degree + 4 years of Experience or PhD + 2 years of experience in Statistics, Mathematics (containing a substantial statistical component), or recognised equivalent to stats MSc

Desirable

Competent statistical programmer (SAS and R)

Knowledge of key technical and regulatory requirements

Experience of design, analysis and reporting of preclinical or clinical studies in more than one setting

Communication skills

Experience and knowledge of statistical methods and applications in study design, analysis and interpretation

Collaboration required

Ability to apply statistical expertise to problems, problem solving and quality focus

When we put unexpected teams in the same room, we ignite bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our outstanding and ambitious world!

Why AstraZeneca

Here, curiosity powers progress—teams are encouraged to follow the science, question assumptions, and push boundaries to transform molecules into medicines that change clinical practice. With a robust pipeline across multiple cancer indications and a history of bringing new therapies to patients, we combine groundbreaking technology with an entrepreneurial spirit and a collaborative community that spans leading medical centers worldwide. We value kindness alongside ambition, unite teams to unlock ambitious thinking, and back critical, high-quality science with sustained investment so your contributions translate into real impact for patients.

The annual base pay for this position ranges from $119,848.00 - $179,772.00. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted 29-Oct-2026

Closing Date 13-Nov-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.