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Informatics Senior Data Scientist

Paradigm

Remote (US) · Posted November 2, 2026

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  • Python
  • SQL

About the job

Paradigm Health is rebuilding the clinical research ecosystem by enabling equitable access to trials for all patients. Our platform enhances trial efficiency and reduces the barriers to participation for healthcare providers. Incubated by ARCH Venture Partners and backed by leading healthcare and life sciences investors, Paradigm’s seamless infrastructure implemented at healthcare provider organizations, will bring potentially life-saving therapies to patients faster.

Our team hails from a broad range of disciplines and is committed to the company’s mission to create equitable access to clinical trials for any patient, anywhere. Join us, and bring your expertise, passion, creativity, and drive as we work together to realize this mission.

Please Note: We are posting this position in anticipation of a hiring need later this year; as such we are NOT in an active recruiting cycle for it, but starting the process of advertising the role to attract talent and applications for those who are interested in future opportunities like this at Paradigm Health.

Role Summary:

We are seeking a skilled and detail-oriented Information/Data Scientist to join our team. The ideal candidate will have a strong background in biomarker and clinical data pipelines, data analysis, and data profiling, with proven expertise in managing and analyzing biological and genomic data. In this role, you will play a critical part in designing, building, and executing terminology libraries, ensuring end-to-end data integrity across our products. You will help organize and represent clinical knowledge within our content management platform, supporting knowledge bases built from or aligned with industry-standard controlled vocabularies, value sets, and ontologies.

What You’ll Do:

Work cross-functionally to perform source-to-target mappings between incoming data (ex. EHR) and our data model

Help develop scalable models to automate mapping source-to-target data

Evaluate and validate data from various sources to ensure accuracy, completeness, and reliability

Contribute to the development and extension of ontologies, vocabularies, and data standards that underpin our platform

Identify and evaluate informatics tools, databases, and content sources to enhance the product user experience

Perform quality control checks and become proficient in querying data stored in our regulatory-grade platform

Provide critical input into the design of data architectures, algorithms, and analysis workflows

Who You Are:

Strong expertise in bioinformatics, clinical data science, or a related field.

Experience with biomarker and/or genomic ontologies or terminologies

Familiarity with healthcare ontologies or terminologies (ICD, SNOMED, LOINC, et al)

Experience with evaluating and ensuring data quality (e.g., completeness, accuracy)

Possess a collaborative mindset, an eagerness to learn, and a high integrity work ethic

Preferred Skills:

Experience with oncology research or clinical genomic applications

Experience with data science tools, programming languages (e.g., Python, R, SQL)

At Paradigm Health, we are committed to providing equal employment opportunities to all qualified individuals. We encourage and welcome candidates from all backgrounds and perspectives to apply for our open positions. We are interested in all qualified individuals and ensure that all employment decisions are based on job-related factors such as skills, experience, and qualifications.