Associate Scientist, Drug Formulation

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition from leading workplace and culture organizations, including Science's Top Employers, Great Place To Work® in the U.S., and Fortune's Best Workplaces in BioPharma.

For patients, for each other, and for the future of science, we’re in. Are you?

About the Role: We’re looking for an Associate Scientist, Drug Formulation on the Research team to help us expand what’s possible for patients with serious diseases. Reporting to the Senior Scientist, Formulation, you’ll focus on the development, optimization, and characterization of nanoparticle (NP)-based drug delivery systems. You will be part of a multidisciplinary team engaged in non-viral vehicle formulation and characterization, supporting platform build and project-level activities.

What You'll Do:

In this role, you’ll have the opportunity to contribute to the advancement of RNA/gene-based therapeutic programs through hands-on formulation science and rigorous analytical evaluation. You’ll also:

Work on formulation and characterization of lipid nanoparticles (LNPs) and other nanoparticle-based delivery systems for platform development and project support

Design and execute formulation studies, including nucleic acid encapsulation into nanoparticle systems, analytical testing, and stability evaluations to finalize formulation compositions for RNA/gene-based therapies

Perform comprehensive physicochemical characterization of nanoparticle formulations, including size, polydispersity index (PDI), surface charge (zeta potential), encapsulation efficiency, drug loading, and release kinetics

Apply a broad set of analytical techniques such as DLS, NTA, UV-Vis spectroscopy, SEC, SDS-PAGE, HPLC, and fluorescence-based assays to evaluate nanoparticles and drug products

Synthesize and develop nanoparticle-based formulations for various therapeutic areas

Support design, synthesis, and purification of protein bioconjugates, including monoclonal antibody and peptide bioconjugation and dye conjugation, as applicable

Characterize and evaluate bioconjugates, including physicochemical properties, stability, conjugation efficiency, and binding ability

Collaborate with team members to troubleshoot formulation challenges and propose data-driven solutions

Perform data and statistical analyses using Excel and GraphPad Prism

Maintain accurate, detailed, and timely records in electronic notebooks and generate internal technical reports

Who You Are:

Basic Qualifications

You meet one of the following minimum education and experience requirements:

Master's degree in Pharmaceutics, Chemistry, Biomedical Engineering, Chemical Engineering, or a related field; OR

Bachelor's degree and 2 years of experience in Pharmaceutics, Chemistry, Biomedical Engineering, Chemical Engineering, or a related field

You are or you also have:

Hands-on experience in nanoparticle-based formulation development and analytical characterization

Preferred Qualifications:

Prior work with nucleic acid delivery systems, especially lipid-based or polymeric nanoparticles

Experience with nucleic acid encapsulation techniques

Experience with bioconjugate and targeted delivery

Proficient in physicochemical and biochemical characterization techniques, including: Dynamic Light Scattering (DLS), Nanoparticle Tracking Analysis (NTA)

Size Exclusion Chromatography (SEC)

UV-Vis Spectroscopy, HPLC, SDS-PAGE

Fluorescence-based assays, protein quantification methods

Strong data analysis and interpretation skills using GraphPad Prism, Excel, or similar tools

Familiarity with stability testing, release profiling, and formulation optimization

Demonstrated ability to independently design, execute, interpret, and present experimental results

Experience in data processing, analysis, statistics, and data interpretation

Where You’ll Work

This role is based out of our Bridgewater, NJ office and requires full-time, in-person presence to support hands-on collaboration, access specialized equipment, and/or operational needs.

Travel Requirements

Minimal travel expected

#LI-BA

#LI-ONSITE

Pay Range: $103,000.00-131,000.00 Annual

Life at Insmed

At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.

Highlights of our U.S. offerings include:

Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)

Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration

401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance

Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities

Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

Eligibility for specific programs may vary and is subject to the terms and conditions of each plan.

Current Insmed Employees: Please apply via the Jobs Hub in Workday.

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. For more information, please refer to our Equal Employment Opportunity and Non-Discrimination Statement on our Careers site.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

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Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at TotalRewards@insmed.com and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.

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