Software Engineer II
Genalyte
San Diego, CA · Posted August 28, 2026
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Where San Diego, CA ranks
Where San Diego, CA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #1Cities hosting the most business conferences in the West Coast78 conferences · of 17
- #2Cities hosting the most human resources conferences6 conferences · of 10
- #3Best cities for life sciences and biotech jobs454 openings · of 41
- #3Best cities for aerospace and defense jobs377 openings · of 67
- #3Cities hosting the most legal services conferences7 conferences · of 17
- #3Cities hosting the most staffing & human capital conferences6 conferences · of 8
Rankings about engineering jobs
- Best cities for software and engineering jobs #1 San Francisco (3,412 openings)
- Best cities for engineering pay after cost of living #1 San Mateo ($216k)
- Most requested AI skills in engineering jobs #1 AI tools in daily work (6.1%)
- AI tools named most often in engineering jobs #1 Claude (1.7%)
- Employers with the most engineering jobs #1 Amazon (2,992 roles)
Pay compared with the market
This listing does not state pay. Across 108 open software engineer ii listings that state pay, the middle half runs $121,000 to $156,500 and the median is $145,000.
Listed pay is what employers advertise, not what people are paid.
How AI is used in this kind of work
Among software developers, AI is already used for some of the tasks. Measured exposure for software developers: 29% (some).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
Skills this job asks for
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About the job
ABOUT GENALYTE At Genalyte, we’re revolutionizing diagnostic testing to empower a healthier future. Genalyte is a San Diego-based diagnostics company developing the Merlin platform, a novel photonic ring resonator-based system designed to deliver rapid, multiplexed diagnostic results. We believe that timely and accurate health insights shouldn’t be a luxury, but a necessity. We are driven by a vision where advanced diagnostic capabilities are accessible, efficient, and seamlessly integrated into healthcare. Genalyte is more than just a laboratory; we are advocates for health empowerment, dedicated to providing insights that can transform lives and communities. WHY WORK FOR US Joining Genalyte at this pivotal pre-commercial stage means your work will have real, visible impact — on our technology, our culture, and ultimately on how diagnostic testing is delivered to patients. Regardless of your role, you'll be part of a collaborative team working closely with leadership to build something meaningful from the ground up. Genalyte offers competitive compensation including base salary, significant equity participation, and a comprehensive benefits package. This is a rare opportunity to grow alongside a high-impact company at a genuinely exciting moment in its journey. POSITION SUMMARY We are seeking a highly motivated Software Engineer II to join our dynamic team at a leading biomedical device company. This position will involve designing and developing software systems and tools as part of a team. Focus will be on developing embedded software to power our Merlin blood-testing product and future product versions, adhering to medical device standards for software quality. The instrument also interfaces with a cloud-hosted platform for data management and test coordination, so experience with device-to-cloud interfaces will be valuable. ESSENTIAL FUNCTIONS & RESPONSIBILITIES These may include but are not limited to: Developing software components and participating in integration of software components Developing software tools to facilitate software test and integration activities Developing and executing software test protocols and generating test reports Troubleshooting issues related to system functionality and performance Contributing to cross-functional teams Mentoring more junior engineers TECHNICAL KNOWLEDGE Familiarity with embedded software system design and concepts Experience with one or more programming languages such as C/C++/C#/Python, especially .NET Experience with build systems, unit testing and general best practices in SW development Proficient knowledge of networking and familiarity with Unix and Windows operating systems Competent in use of requirements management and issue tracking systems like Jira/Confluence Experience with low-level controllers and software interfaces to physical components like motors, robots, and sensors EDUCATION, EXPERIENCE, KNOWLEDGE, SKILLS & ABILITIES Bachelor’s degree in Computer Science, Computer Engineering, Electrical Engineering, or similar field Strong analytical and problem-solving skills Excellent communication and teamwork abilities Ability to author and present technical documents Familiarity with Agile, Scrum, and Waterfall methodologies Experience in life sciences industry and medical device development is a strong preference Demonstrated ability to work productively in a team environment PHYSICAL REQUIREMENTS & WORK ENVIRONMENT This is a primarily office-based role in San Diego, CA. On-site work is required most days because of the necessary access to physical instruments for development, testing, and troubleshooting. Instruments may be located in hardware or wet lab environments that require personal protective equipment and adherence to related protocols. TRAVEL REQUIREMENTS Travel to customer or partner sites could occur, but is not a normal part of this role and would be rare (<1%). COMPENSATION The base salary range for this role is $107,000 - $125,000 per year. Individual pay may vary based on job-related skills, experience, and relevant education or training. In addition to base salary, this role includes meaningful equity participation, eligibility for the annual target bonus plan, and a comprehensive benefits package (health, dental, vision, and flexible time off policy). EQUAL EMPLOYMENT OPPORTUNITY Genalyte, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other legally protected characteristic.