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Senior Director, Enterprise Operations

Lyra Health

Listing collected from Lyra Health's career site. NextChapter is independent of Lyra Health.

United States · $211k–$265k a year · Posted November 4, 2026

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About the job

About Lyra Health Lyra Health is a leading provider of evidence-based mental health care, serving more than 20 million people globally in partnership with employers and more than 100 million through health plan and partner relationships. The company has delivered more than 15 million sessions of mental health care, published more than 35 peer-reviewed studies, and delivered unmatched outcomes in terms of access, clinical effectiveness, and cost efficiency. Extensive peer-reviewed research confirms Lyra’s transformative care model helps people recover twice as fast and results in a 26% annual reduction in overall healthcare claims costs. Lyra is transforming access to life-changing mental health care through Lyra Empower, the only fully integrated, AI-powered platform combining the highest-quality care and technology solutions.

About The Role

We are seeking a Senior Director, Enterprise Operations to drive a step-function improvement in Lyra’s internal operating leverage and effectiveness. Reporting to the Chief Clinical Operations Officer and working in close partnership with the Chief Information Officer, you will build and execute an enterprise-wide strategy aimed to transform our operating cadence, optimize operational efficiency, and embed AI-driven workflows across all core business functions.

What You’ll Do:

Define Lyra’s multi-year enterprise transformation strategy, prioritizing high-impact initiatives that transform Lyra’s pace of delivery and optimize our internal operations

Drive forward Lyra’s enterprise transformation roadmap, taking cross-functional projects from concept to measurable operational outcome

Establish transformation KPIs (e.g., productivity lift, cost-to-serve reduction, throughput velocity) and track realized ROI against Finance benchmarks

Proactively identify key blockers towards success and identify investments required to accelerate impact

Lead a cross-functional team of strategic operators to drive forward operational transformation projects and partner closely with our dedicated technical teams to bring the technical initiatives to life

Enable a high-performing work culture oriented towards ongoing operational excellence and AI fluency

Requirements:

Leadership Experience: 15+ years of overall business experience, including 8+ years leading large-scale operational or digital transformations at growth-stage or enterprise tech companies

Organizational and Process Redesign: Proven experience identifying key blockers to organizational effectiveness, scoping out potential paths forward, building alignment on the solution, and executing

AI & Tech Capabilities: Proven track record deploying enterprise AI solutions, automation workflows, and/or advanced analytics to drive operating leverage

Financial & Analytical Rigor: Deep expertise in financial modeling, business case development, and tracking post-implementation ROI alongside Finance

Change Management: Demonstrated success leading cross-functional teams through complex organizational and workflow shifts.

Leadership Approach: Strategic executor who thrives in fast-paced, high-growth, and ambiguous environments and is an effective communicator across organizations

" We are an Equal Opportunity Employer. We do not discriminate on the basis of race, color, religion, sex (including pregnancy), national origin, age, disability, genetic information or any other category protected by law.

By applying for this position, you acknowledge that your personal information will be processed as per the Lyra Health Workforce Privacy Notice . Through this application, to the extent permitted by law, we will collect personal information from you including, but not limited to, your name, email address, gender identity, employment information, and phone number for the purposes of recruiting and assessing suitability, aptitude, skills, qualifications, and interests for employment with Lyra. We may also collect information about your race, ethnicity, and sexual orientation, which is considered sensitive personal information under the California Privacy Rights Act (CPRA) and special category data under the UK and EU GDPR. Providing this information is optional and completely voluntary, and if you provide it you consent to Lyra processing it for the purposes as described at the point of collection, for example for diversity and inclusion initiatives. If you are a California resident and would like to limit how we use this information, please use the Limit the Use of My Sensitive Personal Information form . This information will only be retained for as long as needed to fulfill the purposes for which it was collected, as described above. Please note that Lyra does not “sell” or “share” personal information as defined by the CPRA. Outside of the United States, for example in the EU, Switzerland and the UK, you may have the right to request access to, or a copy of, your personal information, including in a portable format; request that we delete your information from our systems; object to or restrict processing of your information; or correct inaccurate or outdated personal information in our systems. These rights may be subject to legal limitations. To exercise your data privacy rights outside of the United States, please contact globaldpo@lyrahealth.com . For more information about how we use and retain your information, please see our Workforce Privacy Notice ."

211000 - 265000 USD a year

As a full-time Senior Director, Enterprise Operations, you will be employed by Lyra Health, Inc. The anticipated annual base salary range for this full-time position is $211,000 to $265,000. The base range is determined by role and level, and placement within the range will depend on a number of job-related factors, including but not limited to your skills, qualifications, experience and location. This role may also be eligible for discretionary bonuses.

Annual salary is only one part of an employee’s total compensation package at Lyra. We also offer generous benefits that include:

Comprehensive healthcare coverage (including medical, dental, vision, FSA/HSA, life and disability insurances)

Lyra for Lyrians; coaching and therapy services

Equity in the company through discretionary restricted stock units

Competitive time off with pay policies including vacation, sick days, and company holidays

Paid parental leave

401K retirement benefits

Monthly tech allowance

We like to spread joy throughout the year with well-being perks and activities, surprise swag, regular community celebration…and more!

We can’t wait to meet you.