Executive Director, IT Commercial
Immatics N.V.
Listing collected from Immatics N.V.'s career site. NextChapter is independent of Immatics N.V..
Remote · Houston, TX · Posted September 25, 2026
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About the job
Join Immatics and shape the future of cancer immunotherapy; one patient at a time! Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. Why Join Us? Innovative Environment: Help to pioneer advancements in cancer immunotherapy. Collaborative Culture: Be part of a diverse team dedicated to your professional growth. Global Impact: Contribute to therapies that make a lasting impact on patients globally. Role Overview Immatics is seeking a strategic and highly collaborative Executive Director, IT Commercial to establish and lead the IT Commercial & Patient Operations function. The Executive Director, IT Commercial will enable our US commercial launch strategy and drive IT launch milestones. This impactful leader will own the end-to-end IT Commercial and Medical Affairs roadmap, from commercial systems and patient operations platforms to the commercial data foundation, sequencing delivery against business milestones. The Executive Director, IT Commercial is the bridge between the US Commercial organization and global IT, translating functional needs into an executable, governed technology portfolio, with stakeholder engagement spanning Market Access, Patients Operations, Sales, Marketing, Commercial Analytics & Operations, as well as Medical Affairs. This leader will create the strategy and continuous development of our commercial IT landscape. Reports to: Vice President, IT Location: Remote Salary Range: $245,000 - $275,000 Basic Qualifications: Bachelor’s degree in computer science, information systems, life sciences, or a related field, or equivalent experience. 15+ years of IT experience in the pharmaceutical or biotech industry, including 7+ years in senior leadership roles. Preferred Qualifications: Advanced degree in computer science, information systems, life sciences, or a related field. Proven track record leading IT for at least one US commercial product launch readiness, ideally as IT launch lead. Deep knowledge of the commercial and medical affairs pharma systems landscape. Knowledge and background in Cell & Gene therapy is strongly preferred Experience establishing commercial data foundations, including Master Data Management, integrations, data warehouse/lake, reporting, and analytics. Working knowledge of GxP/CSV, 21 CFR Part 11, and healthcare data privacy requirements, including HIPAA. Demonstrated ability to build and lead teams, manage vendors and budgets, and deliver a multi-project portfolio against fixed regulatory milestones. Ability to communicate complex problems to effectively communicate business needs to stakeholders and end-users. Executive presence and high emotional intelligence; able to influence and align senior leaders and stakeholders without formal authority. Strong governance, prioritization, and decision-making capabilities in a multi-project environment with hard milestones. In this role, you will: Own, refine, and execute the IT Commercial & Patient Operations strategy and roadmap, aligning system rollouts with commercial milestones and managing dependencies across functions, vendors, and global IT. Deliver the commercial systems portfolio, including ecosystem expansion, sales operations, marketing hub, omnichannel engagement, patient operations, commercial analytics, market access hub and medical affairs. Deliver the patient operations technology stack, including ATC portal, hub and patient services integrations, CRM, allocation and slot management, call center/telephony, and end-to-end patient and product journey tracking. Establish the commercial data foundation, including master data management, commercial data warehouse and data lake, reporting and analytics, and AI-enabled use cases. Drive integrations with enterprise systems Ensure compliance of all commercial and patient-facing systems with GxP/CSV requirements, 21 CFR Part 11, SOX, transparency reporting, HIPAA, GDPR, and applicable cybersecurity requirements. Manage vendors, external partners, and implementation providers across the commercial portfolio, including contract, budget, and performance management. What do we offer? At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics Comprehensive Benefits : Competitive rates for Health, Dental, and Vision Insurance 4 weeks of vacation, granted up front each year and prorated for first and last year of employment. 12 company paid holidays 7 days of sick time 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars 100% employer-paid short- and long-Term disability coverage 401(k) with immediate eligibility and company match. The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment. Partially paid parental leave for eligible employees. Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance. Equal Employment Opportunity We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law. Reasonable Accommodations We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at RecruitingUS@immatics.com . Work Authorization Applicants must be authorized to work in the United States without the need for current or future sponsorship. Pre-Employment Requirements Employment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.