This listing pays about $300,000 a year. Across 80 open medical director listings that state pay, the middle half runs $219,500 to $300,000 and the median is $268,500. That is inside the middle half of those listings, 12% above the median.

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About the job

Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need. As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at ScholarRock.com and follow @ScholarRock on X and on LinkedIn.

Summary of Position:

Position Responsibilities:

Provide medical leadership for clinical development activities of assigned pipeline products, including leading efforts to define clinical development strategy and plan

Collaborate with other members of the development and research teams to contribute to building a collaborative culture and improving effectiveness of the development team

Serve as subject matter expert, leading efforts to provide scientifically robust evaluation of development strategy and plans, including robust literature review to perform disease area assessment, development landscape analysis, and development and regulatory pathway evaluation

Engage with external scientific and clinical trial experts, clinical and regulatory consultants, to develop scientifically robust clinical study design

Provide hands-on authoring of clinical and regulatory documents, including study concepts, protocols, investigator brochures, regulatory documents, publications, etc.

Serve as lead author in clinical responses to regulatory authorities, related to review of protocols, INDs, BLA/MAA/JNDA, and other regulatory filings

Provide medical leadership and input in cross-functional team activities, including business development activities, non-clinical development, quality assurance, clinical operations, biostatistics, regulatory affairs and drug safety

Responsible for medical oversight of clinical trials, including medical monitoring of studies, adverse event reporting, and patient safety for all clinical trials across a development program.

Provide medical and scientific leadership in data analysis and interpretation, maintaining integrity, scientific rigor, and transparency

Work within compliance to all applicable GCP/ ICH regulations

Candidate Requirements:

MD, MD/PhD, or equivalent, based in greater Boston

Ability to be present regularly in the Cambridge MA office

Strong critical thinking skills, with ability to synthesize complex information, and exceptional communication skills, both verbal and written

5+ years of experience in the biopharmaceutical industry, with 3+ years of clinical development experience; neuromuscular or rare disease experience preferred but not required

Highly organized, outcome-oriented, self-motivated team player with strong interpersonal skills and effective conflict management skills

Experience in innovative clinical study design, analysis of clinical data, publications, and working knowledge of biostatistics and pharmacokinetics/pharmacodynamics

Understanding of the drug development process from pre-IND through BLA

Experience interacting with health authorities in the US and EU

In-depth knowledge of ICH-GCP and other application regulatory guidelines

Ability to travel domestically and internationally (~15%)

Scholar Rock is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.