Software Engineer
Periodic Labs
Menlo Park, CA · Posted February 10, 2026
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Where Menlo Park, CA ranks
Where Menlo Park, CA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #5Best cities for AI-skill jobs in the West Coast32% · of 71
- #6Best cities for financial services pay after cost of living$164k · of 33
- #6Best cities for AI-skill jobs32% · of 100
- #7Best cities for entry-level jobs that want AI skills in the West Coast21% · of 54
- #11Best all-round cities for AI careers in the West Coast75 / 100 · of 39
- #12Best cities for pay after cost of living in California$169k · of 32
Rankings about engineering jobs
- Best cities for software and engineering jobs #1 San Francisco (3,412 openings)
- Best cities for engineering pay after cost of living #1 San Mateo ($216k)
- Most requested AI skills in engineering jobs #1 AI tools in daily work (6.1%)
- AI tools named most often in engineering jobs #1 Claude (1.7%)
- Employers with the most engineering jobs #1 Amazon (2,992 roles)
Pay compared with the market
This listing does not state pay. Across 816 open software engineer listings that state pay, the middle half runs $150,000 to $247,000 and the median is $192,500.
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How AI is used in this kind of work
Among software developers, AI is already used for some of the tasks. Measured exposure for software developers: 29% (some).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
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About the job
ABOUT PERIODIC LABS
We’re an AI and physical sciences company building state-of-the-art models to accelerate breakthroughs across materials, energy, and beyond. Backed by world-class investors and growing rapidly, we operate at the pace the frontier requires. Our team brings deep expertise, genuine ownership, and an insatiable drive to push the boundaries of what’s scientifically possible.
ABOUT THE ROLE
We’re hiring software engineers to build the backend and distributed systems that form the software backbone of an AI-native physical science lab. These systems turn scientific intent into reliable execution: scheduling large simulation workloads, orchestrating experiments and shared equipment, and connecting instruments and automation to the rest of our software. Depending on your background and interests, you may work across simulation infrastructure, lab orchestration, or automation systems. You do not need prior experience in every area. We care most about strong engineers who can reason about complex systems, make failure visible, and build software that remains reliable as scientific work scales. You’ll work directly with scientists, infrastructure engineers, and lab engineers to understand how research gets done, then turn prototypes and manual workflows into robust systems without slowing down discovery.
WHAT YOU’LL DO
- Design and build backend and distributed systems that execute scientific work reliably.
- Build scheduling and orchestration for long-running workflows across compute clusters, instruments, and other shared resources.
- Create clear APIs, data models, and service boundaries connecting research software, lab information systems, instruments, and automation.
- Make execution inspectable and recoverable through durable state, retries, failure handling, observability, and provenance.
- Turn promising research prototypes and scientific workflows into maintainable production systems.
- Diagnose bottlenecks and failures across application code, infrastructure, data, and hardware integrations.
- Work closely with scientists and engineers to improve experimental throughput, reliability, and reproducibility.
YOU WILL THRIVE IN THIS ROLE IF YOU HAVE EXPERIENCE WITH
- Strong software engineering fundamentals and a track record of building production backend or distributed systems.
- Experience with asynchronous or long-running work, such as batch jobs, workflow orchestration, data pipelines, schedulers, or shared-resource systems.
- The ability to reason clearly about concurrency, idempotency, partial failures, consistency, and resource contention.
- Experience designing maintainable APIs and data models for complex systems.
- Strong debugging skills across services, infrastructure, dependencies, and data.
- Comfort working with technical collaborators to turn ambiguous needs into reliable systems.
ESPECIALLY STRONG CANDIDATES MAY ALSO HAVE
You do not need experience in every area below. Depth in one or more may help us identify where you can have the greatest impact.
- Large-scale batch or distributed compute, scientific simulation, GPU workloads, or ML infrastructure.
- Workflow engines, DAG orchestration, job schedulers, or cluster execution systems.
- LIMS, MES, ERP, process-control systems, lab informatics, or scientific data management.
- Robotics, hardware controls, instrument drivers, vendor APIs or SDKs, or industrial automation.
- Experience in a physical lab, manufacturing environment, or materials-science setting.
MECHANICS
Minimum education: Bachelor’s degree or similar experience
Location: Menlo Park, CA
Compensation: $250,000-350,000 + equity
Visa sponsorship: Yes, we sponsor visas.