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About the job

At Avalo (ahh-vah'-low), we are 100% focused on developing treatments for immune-mediated inflammatory diseases with large unmet needs that affect millions worldwide. Our strategy is to develop medicines that target the IL-1β pathway, which is a central driver of the inflammatory process.

We share a commitment to teamwork, passion for science, and dedication to patients suffering from acute and chronic inflammatory disorders. Our collective expertise in discovery, development, and regulatory approvals is evidenced in our strong individual track records of advancing multiple therapeutic programs to successful commercialization.

Position Summary:

This individual will serve as the commercial architect for Avalo's first potential product launch. The successful candidate will be responsible for developing and executing global and U.S. launch readiness plans, shaping brand strategy, generating deep customer insights, building commercial capabilities, and partnering cross-functionally to maximize the value of the HS franchise.

This highly visible leadership role requires a strategic thinker who can operate effectively in a fast-paced biotechnology environment while balancing long-term commercial vision with hands-on execution. The individual will work closely with Clinical Development, Medical Affairs, Market Access, Regulatory Affairs, Investor Relations, Business Development, and external partners to position Avalo for a successful commercialization and growth trajectory.

Essential Duties and Responsibilities:

Commercial Strategy & Brand Leadership

• Advance and lead the overall commercial strategy for abdakibart, Avalo’s lead drug candidate, in Hidradenitis Suppurativa (HS).

• Build the brand vision, positioning, messaging, value proposition, and lifecycle strategy

• Direct market assessment, forecasting, competitive intelligence, and commercial planning activities.

• Translate clinical and scientific data into differentiated customer-focused strategies.

• Identify market opportunities, risks, and competitive dynamics to inform business decisions.

• Serve as the commercial lead on cross-functional program teams.

• Manage external agency partners.

Launch Excellence

• Build and execute comprehensive cross-functional launch readiness plans.

• Establish launch milestones, KPIs, governance structures, and performance tracking mechanisms.

• Lead pre-launch customer engagement and market shaping initiatives.

• Ensure organizational readiness across marketing, sales, market access, patient services, and operations.

• Develop launch scenarios and contingency plans to support evolving clinical and regulatory timelines.

Customer Insights & Market Development

• Generate actionable insights from healthcare providers, patients, payers, advocacy groups, and key opinion leaders.

• Develop customer segmentation and targeting strategies.

• Establish strong relationships with external experts, advocacy organizations and HS stakeholders.

Market Access & Value Strategy

• Partner closely with Market Access to develop payer, reimbursement, and value communication strategies.

• Support pricing, contracting, and access planning efforts.

• Ensure commercial strategies are aligned with payer expectations and patient access objectives.

Cross-Functional Leadership

• Collaborate closely with Clinical Development and operations, HEOR, Medical Affairs, Regulatory Affairs, , Manufacturing, and Supply Chain to ensure commercial perspectives are integrated throughout development.

• Partner with Medical Affairs to optimize scientific communication plans and publication strategies.

• Support investor and board communications regarding the commercial opportunity for abdakibart in HS and launch readiness plans Represent commercial perspectives in governance and strategic planning discussion

Required Education and Experience:

• Bachelor's degree required; advanced degree (MBA, MPH, PharmD, MS, or PhD) preferred.

• 12+ years of biotechnology, pharmaceutical, or healthcare industry experience.

• 5+ years leading launch planning, launch excellence, commercial operations, new product planning, or strategic program management.

• Demonstrated success leading at least one major pharmaceutical or biotechnology product launch.

• Experience coordinating complex, cross-functional initiatives in a matrixed environment.

• Experience in dermatology and/or immunology/inflammation specialty products, preferred.

Preferred Qualifications

• Experience launching biologics or specialty therapies.

• Understanding of HS, dermatology, immunology, or inflammatory disease markets.

• Experience within emerging biotechnology companies and first-launch organizations.

• Familiarity with global launch planning and commercialization frameworks.

About Avalo Therapeutics

Avalo Therapeutics is a clinical stage biotechnology company dedicated to developing therapeutics targeting the IL-1β pathway for immune-mediated inflammatory diseases. Avalo is advancing its lead anti-IL-1β monoclonal antibody (mAb) drug candidate, abdakibart, into a phase 3 registrational program in hidradenitis suppurativa (HS), a chronic inflammatory skin condition that affects an estimated 1–4% of the population globally. Avalo is pursuing additional development opportunities in IL-1β driven indications. Avalo is also developing AVTX-010, a long-acting next-generation anti-IL-1β mAb. For more information about Avalo, please visit www.avalotx.com.

ATTENTION: External Agencies and Placement Firms

A member of the Avalo Human Resources Department will contact an agency directly if an open position is eligible to be sourced from an outside recruiting service. Avalo does not accept unsolicited resumes from employment agencies for any employment opportunity. All agencies/recruiters must have a written agreement/SOW in place with Avalo and prior to submitting any resume or CV.

All resumes must be submitted through the appropriate process. Any resumes submitted without an agreement and/or any resumes sent unsolicited through e-mail accounts of Avalo employees will be considered outside of the appropriate process, do not imply or create any obligation on our part, do not impart any restrictions on Avalo with respect to the hiring of any persons whose resumes are so submitted and are not eligible for placement fees.