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Lead/Principal Software QA Test Engineer

Medpace Holdings

Listing collected from Medpace Holdings's career site. NextChapter is independent of Medpace Holdings.

Cincinnati, OH · Posted November 3, 2026

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  • Onboarding
  • Agile

About the job

Voted a Top Cincinnati Workplace for 4 years running, Medpace is growing rapidly, and we are currently seeking a full-time, office-based Lead Software QA Engineer to join our Information Technology (IT) team. The Medpace IT department creates custom software solutions for our internal and external business users. The Software QA Engineer is responsible for the planning and execution of software testing for one or more of these web-based applications. They will work with developers and end users to understand requirements and write test plans, execute manual and automated tests, and create summary reports. The Lead engineer has additional responsibilities to lead projects, mentor other testers, and support process improvements.

Responsibilities

Lead validation projects of complex software to ensure robust functionality and compliance with regulations;

Lead and mentor junior testers;

Review and analyze functional requirements specifications to provide feedback and ensure requirements are testable;

Create test plans and test cases per documented requirements;

Lead constructive peer review of test cases;

Execute functional test cases to ensure the system is robust and fit for purpose;

Report defects and work with the development team toward resolution of the defects;

Write test summary reports;

Facilitate execution of acceptance test scripts by end users;

Attend and lead regular project meetings (daily stand-ups, refinement meetings, etc.);

Work closely with developers and end users throughout the software life cycle to ensure that applications meet the needs of the users;

Assist management team in formulating and implementing process improvements, including training staff on those processes; and

Lead project initiatives set forth by management outside the context of specific applications.

Qualifications

Bachelor’s degree and 6+ years of experience in software testing, preferably in an agile-like environment;

Experience leading manual testing efforts for complex software applications

Experience communicating and working within cross-departmental teams consisting of software developers, department leads, and end users;

Excellent computer skills;

Excellent analytical thinking skills;

Excellent written and oral communication skills;

Experience with direct personnel supervision is a plus!; and

Experience in the regulated healthcare industry is a plus!

Medpace Overview

Medpace is a full-service clinical contract research organization (CRO) providing phase l-lV clinical development services to the biotechnology, pharmaceutical, and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics through the advancement of clinical research. We leverage in-country regulatory and therapeutic expertise across all major therapeutic areas including oncology, cardiology, metabolic, endocrinology, central nervous system, and anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, we employ more than 6,500 people across 40+ countries.

Why Medpace?

When you join Medpace, you become part of an innovative team that brings cutting-edge therapies to market while building a meaningful and rewarding career focused on scientific excellence and improving patient outcomes around the world through continuous learning and cross-functional collaboration.

Purpose-Driven Work

Work alongside physicians, scientists, and industry-leading experts committed to advancing the global development of medical therapeutics through clinical research excellence

Collaborative Culture

Contribute to an interactive team environment that empowers decision making, creative thinking, and continuous learning through open communication and mutual trust.

Leadership throughout Medpace is both accessible and approachable

Continuous Growth & Development

Office based environment with on-site mentors

Defined career paths with clear advancement opportunities

Industry renowned onboarding and training programs designed to accelerate professional development

Ongoing training and continuous learning opportunities throughout your career

An environment that encourages employees to influence change, contribute ideas, and grow quickly

Other Employee Benefits

Competitive compensation programs that recognize and reward performance

Comprehensive health, wellness, retirement, and PTO benefits

Office based culture with occasional WFH that provides flexibility for eligible positions after training

Company-sponsored social events and intramural sports

Cincinnati Headquarters Experience

A modern corporate campus designed to support collaboration and productivity

Multiple on-site dining options in the heart of Madison Square

Free on-site parking

Convenient access to on-site 24-7 fitness and wellness facilities

What to Expect Next

A Medpace team member will review your application and if your profile matches our current needs, you will be contacted for an interview. While we review all applications carefully, we are unable to respond to every applicant, and only candidates selected for interviews will be contacted.

Lead validation projects of complex software to ensure robust functionality and compliance with regulations;

Lead and mentor junior testers;

Review and analyze functional requirements specifications to provide feedback and ensure requirements are testable;

Create test plans and test cases per documented requirements;

Lead constructive peer review of test cases;

Execute functional test cases to ensure the system is robust and fit for purpose;

Report defects and work with the development team toward resolution of the defects;

Write test summary reports;

Facilitate execution of acceptance test scripts by end users;

Attend and lead regular project meetings (daily stand-ups, refinement meetings, etc.);

Work closely with developers and end users throughout the software life cycle to ensure that applications meet the needs of the users;

Assist management team in formulating and implementing process improvements, including training staff on those processes; and

Lead project initiatives set forth by management outside the context of specific applications.

Bachelor’s degree and 6+ years of experience in software testing, preferably in an agile-like environment;

Experience leading manual testing efforts for complex software applications

Experience communicating and working within cross-departmental teams consisting of software developers, department leads, and end users;

Excellent computer skills;

Excellent analytical thinking skills;

Excellent written and oral communication skills;

Experience with direct personnel supervision is a plus!; and

Experience in the regulated healthcare industry is a plus!