Lead/Principal Software QA Test Engineer
Medpace Holdings
Listing collected from Medpace Holdings's career site. NextChapter is independent of Medpace Holdings.
Cincinnati, OH · Posted November 3, 2026
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Where Cincinnati, OH ranks
Where Cincinnati, OH placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #2Best all-round cities for new graduates in the Midwest64 / 100 · of 20
- #2Best all-round cities for new graduates in the Great Lakes63 / 100 · of 16
- #3Cities with the most jobs that do not need a four-year degree in the Midwest153 jobs · of 51
- #3Cities with the most jobs that do not need a four-year degree in the Great Lakes153 jobs · of 36
- #4Best cities for software and engineering jobs in the Midwest252 openings · of 59
- #4Best cities for software and engineering jobs in the Great Lakes252 openings · of 48
Rankings about engineering jobs
- Best cities for software and engineering jobs #1 San Francisco (3,412 openings)
- Best cities for engineering pay after cost of living #1 San Mateo ($216k)
- Most requested AI skills in engineering jobs #1 AI tools in daily work (6.1%)
- AI tools named most often in engineering jobs #1 Claude (1.7%)
- Employers with the most engineering jobs #1 Amazon (2,992 roles)
How AI is used in this kind of work
Among software quality assurance analysts and testers, AI is already used for a large share of the tasks. Measured exposure for software quality assurance analysts and testers: 52% (high).
Share of this job’s tasks that AI is already used for at work, from real usage. It is not a forecast of job loss, and a low number means no use seen yet. Source: Anthropic Economic Index.
Skills this job asks for
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About the job
Voted a Top Cincinnati Workplace for 4 years running, Medpace is growing rapidly, and we are currently seeking a full-time, office-based Lead Software QA Engineer to join our Information Technology (IT) team. The Medpace IT department creates custom software solutions for our internal and external business users. The Software QA Engineer is responsible for the planning and execution of software testing for one or more of these web-based applications. They will work with developers and end users to understand requirements and write test plans, execute manual and automated tests, and create summary reports. The Lead engineer has additional responsibilities to lead projects, mentor other testers, and support process improvements.
Responsibilities
Lead validation projects of complex software to ensure robust functionality and compliance with regulations;
Lead and mentor junior testers;
Review and analyze functional requirements specifications to provide feedback and ensure requirements are testable;
Create test plans and test cases per documented requirements;
Lead constructive peer review of test cases;
Execute functional test cases to ensure the system is robust and fit for purpose;
Report defects and work with the development team toward resolution of the defects;
Write test summary reports;
Facilitate execution of acceptance test scripts by end users;
Attend and lead regular project meetings (daily stand-ups, refinement meetings, etc.);
Work closely with developers and end users throughout the software life cycle to ensure that applications meet the needs of the users;
Assist management team in formulating and implementing process improvements, including training staff on those processes; and
Lead project initiatives set forth by management outside the context of specific applications.
Qualifications
Bachelor’s degree and 6+ years of experience in software testing, preferably in an agile-like environment;
Experience leading manual testing efforts for complex software applications
Experience communicating and working within cross-departmental teams consisting of software developers, department leads, and end users;
Excellent computer skills;
Excellent analytical thinking skills;
Excellent written and oral communication skills;
Experience with direct personnel supervision is a plus!; and
Experience in the regulated healthcare industry is a plus!
Medpace Overview
Medpace is a full-service clinical contract research organization (CRO) providing phase l-lV clinical development services to the biotechnology, pharmaceutical, and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics through the advancement of clinical research. We leverage in-country regulatory and therapeutic expertise across all major therapeutic areas including oncology, cardiology, metabolic, endocrinology, central nervous system, and anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, we employ more than 6,500 people across 40+ countries.
Why Medpace?
When you join Medpace, you become part of an innovative team that brings cutting-edge therapies to market while building a meaningful and rewarding career focused on scientific excellence and improving patient outcomes around the world through continuous learning and cross-functional collaboration.
Purpose-Driven Work
Work alongside physicians, scientists, and industry-leading experts committed to advancing the global development of medical therapeutics through clinical research excellence
Collaborative Culture
Contribute to an interactive team environment that empowers decision making, creative thinking, and continuous learning through open communication and mutual trust.
Leadership throughout Medpace is both accessible and approachable
Continuous Growth & Development
Office based environment with on-site mentors
Defined career paths with clear advancement opportunities
Industry renowned onboarding and training programs designed to accelerate professional development
Ongoing training and continuous learning opportunities throughout your career
An environment that encourages employees to influence change, contribute ideas, and grow quickly
Other Employee Benefits
Competitive compensation programs that recognize and reward performance
Comprehensive health, wellness, retirement, and PTO benefits
Office based culture with occasional WFH that provides flexibility for eligible positions after training
Company-sponsored social events and intramural sports
Cincinnati Headquarters Experience
A modern corporate campus designed to support collaboration and productivity
Multiple on-site dining options in the heart of Madison Square
Free on-site parking
Convenient access to on-site 24-7 fitness and wellness facilities
What to Expect Next
A Medpace team member will review your application and if your profile matches our current needs, you will be contacted for an interview. While we review all applications carefully, we are unable to respond to every applicant, and only candidates selected for interviews will be contacted.
Lead validation projects of complex software to ensure robust functionality and compliance with regulations;
Lead and mentor junior testers;
Review and analyze functional requirements specifications to provide feedback and ensure requirements are testable;
Create test plans and test cases per documented requirements;
Lead constructive peer review of test cases;
Execute functional test cases to ensure the system is robust and fit for purpose;
Report defects and work with the development team toward resolution of the defects;
Write test summary reports;
Facilitate execution of acceptance test scripts by end users;
Attend and lead regular project meetings (daily stand-ups, refinement meetings, etc.);
Work closely with developers and end users throughout the software life cycle to ensure that applications meet the needs of the users;
Assist management team in formulating and implementing process improvements, including training staff on those processes; and
Lead project initiatives set forth by management outside the context of specific applications.
Bachelor’s degree and 6+ years of experience in software testing, preferably in an agile-like environment;
Experience leading manual testing efforts for complex software applications
Experience communicating and working within cross-departmental teams consisting of software developers, department leads, and end users;
Excellent computer skills;
Excellent analytical thinking skills;
Excellent written and oral communication skills;
Experience with direct personnel supervision is a plus!; and
Experience in the regulated healthcare industry is a plus!