Head of Business Excellence (BE), MA Bio Ops
Takeda Development Center Americas
Lexington, MA · $177k–$278k a year · Posted November 10, 2026
Just laid off? Start here: a plan for the first weeks
Want recruiters in Operations to be able to find you?
Roles at this level, like this one at Takeda Development Center Americas, are often filled through recruiters.
See every open role at Takeda Development Center Americas
More in Massachusetts job market · Pharmaceuticals & Biotech · Operations jobs
More roles at Takeda Development Center Americas
- Global Head of Ethics & Compliance, R&D Business Partner · Boston, MA
- Medical Director, Clinical Science, Neuroscience TAU- Psychiatry · Cambridge, MA
- Senior Director, Oncology Forecasting · Boston, MA
- Director, Patient Engagement, Experience and Recruitment
- Senior Director, AIRx DMPK & Modeling Lead · Boston, MA
- Senior Director, Search and Evaluation Lead, Global Oncology · Cambridge, MA
Similar jobs
- Head of Supply Chain · Tutor Intelligence · Watertown, MA
- Head of Quality · Tutor Intelligence · Watertown, MA
- Executive Director, Supply Chain & External Manufacturing · Prime Medicine · Cambridge, MA
- Head of US Strategic Initiatives and Operations · Astrazeneca · Boston, MA
- Executive Director, Medical Affairs Operations & Strategic Excellence · Viridian Therapeutics · Waltham, MA
- Executive Director, Clinical and Commercial Global Supply Chain · Deciphera Pharmaceuticals · Waltham, MA
Where Lexington, MA ranks
Where Lexington, MA placed in our monthly rankings, month by month. Each month stays online at its own address.
November 2026
- #2Best cities for entry-level jobs that want AI skills in the Northeast19% · of 48
- #2Best cities for entry-level jobs that want AI skills in New England19% · of 20
- #3Best all-round cities for mid-career professionals in New England65 / 100 · of 11
- #4Best cities for pay after cost of living in New England$162k · of 11
- #4Best cities for pay after cost of living in Massachusetts$162k · of 9
- #4Best cities for software and engineering jobs in New England114 openings · of 24
Rankings about operations jobs
- Best cities for operations jobs #1 New York (1,429 openings)
- Best cities for operations pay after cost of living #1 Reston ($177k)
- Most requested AI skills in operations jobs #1 AI tools in daily work (2.5%)
- AI tools named most often in operations jobs #1 Claude (0.28%)
- Employers with the most operations jobs #1 Amazon (1,480 roles)
Skills this job asks for
Say which you have and which you want to build. We use it to match you to jobs like this one.
About the job
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge.
Job Description
About the role:
The Head of Business Excellence (BE) leads the site BE function and drives improvements in MA Bio Ops performance in alignment with site and Takeda strategies. The BE function includes Operational Excellence (OE), Portfolio and Project Management (PPM), and Learning (GxP, Non-GxP and reskilling) teams, as well as the Enterprise Risk Management, Crisis Management and Business Continuity processes. The BE Head owns strategy deployment and implementation of Takeda’s Agile Operating System (AOS) methodologies. The role drives value creation projects, leads the site Continuous Improvement (CI) system, and fosters a culture of quality, safety and continuous improvement. The Head of BE is a member of the Site Leadership Team (SLT) and responsible for a function of up to 20 employees. This role is accountable for delivering 3% to 5% COP (Core Operating Profit) of addressable savings annually and ensuring GxP and non-GxP training KPIs are maintained at 90% and 95% respectively.
How you will contribute:
Partners with Site Head and SLT to develop and maintain site’s long-term strategic plan and vision
Lead Strategy Deployment process to translate strategic priorities into actionable initiatives & measures
Develop and execute functional strategy and initiatives for OE, PPM and Learning, aligned to site goals
Partner closely with operational teams to effectively execute OE, PPM and Learning strategies
Leads site programs and develops recommendations to align future site investments to business needs
Design SLT governance to support cross-functional alignment, decision-making & progress on site goals
Maintain and improve tiered accountability system to achieve site goals and performance outcomes
Foster a performance culture of accountability with metrics and KPIs
Ensures appropriate portfolio performance management and monitoring at the site level
Supports Site Head with executive-level content for network business reviews and escalations
Oversee and lead OE initiatives to improve business outcomes using AOS, digital & automation
Champion continuous improvement, Lean, Six Sigma and Booster methodologies, as required
Use data driven approach to drive highest impact improvements in process, cost & speed
Collaborate closely with HR and Finance to translate process improvements into workforce plans
Be an ambassador for Organizational Change Management (OCM) e3+ framework across the site.
Coach leadership teams on lean methodologies (AOS) and problem-solving elements to drive value
Develop and deliver program to build site-wide lean and six-sigma capabilities and learning program
Develop and execute site Learning roadmap to deliver future-ready capabilities, including digital fluency
Ensure plans are in place to deliver all required training (GxP & Non-GxP) via role-based curricula
Effectively partner with global learning leads and Quality to deliver required GSQ learning strategies
Monitor training KPIs monthly and work with SLT on action plans to address gaps.
Partners with global functions and BE community to implement applicable network initiatives
Align site initiatives with Quality and EHS to ensure regulatory and compliance requirements are fulfilled
Manage response to external productivity assessments (e.g. POBOS) and internal business audits (GIA)
Oversees site performance management process: monitors KPIs, identifies gaps, recommends actions
Facilitate site Crisis Management Team process & annual exercises to ensure leaders are trained
Manages the approved BE functional budget and resources
Minimum Requirements/Qualifications:
Minimum of 8+ years of experience in operational management roles, with a strong focus on GxP regulations, Operational Excellence, Continuous Improvement, or Lean Manufacturing.
Bachelor’s degree in relevant field (e.g. engineering, business) or equivalent work-experience
Advanced knowledge of lean management and problem-solving methodologies; Green Belt certification
Preferred
A master's degree (MBA, M.Sc.)
Experience with learning management systems in a regulated cGMP manufacturing environment
Experienced people leader, with proficiency in coaching
Knowledge of emerging digital technology, data analysis & manufacturing software (e.g., SAP, MES, etc.)
Project Management certification (e.g. PMP, sAFE, or similar).
Experience with strategy deployment/management.
Black Belt certification or equivalent.
Development during the role: Build advanced competencies on AOS during role.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location: USA - MA - Lexington - BIO OPS
U.S. Base Salary Range: $177,000.00 - $278,080.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
For information about our benefits, please click here .
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations USA - MA - Lexington - BIO OPS
Worker Type Employee
Worker Sub-Type Regular
Time Type Full time
Job Exempt Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.