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Head of Business Excellence (BE), MA Bio Ops

Takeda Development Center Americas

Lexington, MA · $177k–$278k a year · Posted November 10, 2026

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About the job

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Job Description

About the role:

The Head of Business Excellence (BE) leads the site BE function and drives improvements in MA Bio Ops performance in alignment with site and Takeda strategies. The BE function includes Operational Excellence (OE), Portfolio and Project Management (PPM), and Learning (GxP, Non-GxP and reskilling) teams, as well as the Enterprise Risk Management, Crisis Management and Business Continuity processes. The BE Head owns strategy deployment and implementation of Takeda’s Agile Operating System (AOS) methodologies. The role drives value creation projects, leads the site Continuous Improvement (CI) system, and fosters a culture of quality, safety and continuous improvement. The Head of BE is a member of the Site Leadership Team (SLT) and responsible for a function of up to 20 employees. This role is accountable for delivering 3% to 5% COP (Core Operating Profit) of addressable savings annually and ensuring GxP and non-GxP training KPIs are maintained at 90% and 95% respectively.

How you will contribute:

Partners with Site Head and SLT to develop and maintain site’s long-term strategic plan and vision

Lead Strategy Deployment process to translate strategic priorities into actionable initiatives & measures

Develop and execute functional strategy and initiatives for OE, PPM and Learning, aligned to site goals

Partner closely with operational teams to effectively execute OE, PPM and Learning strategies

Leads site programs and develops recommendations to align future site investments to business needs

Design SLT governance to support cross-functional alignment, decision-making & progress on site goals

Maintain and improve tiered accountability system to achieve site goals and performance outcomes

Foster a performance culture of accountability with metrics and KPIs

Ensures appropriate portfolio performance management and monitoring at the site level

Supports Site Head with executive-level content for network business reviews and escalations

Oversee and lead OE initiatives to improve business outcomes using AOS, digital & automation

Champion continuous improvement, Lean, Six Sigma and Booster methodologies, as required

Use data driven approach to drive highest impact improvements in process, cost & speed

Collaborate closely with HR and Finance to translate process improvements into workforce plans

Be an ambassador for Organizational Change Management (OCM) e3+ framework across the site.

Coach leadership teams on lean methodologies (AOS) and problem-solving elements to drive value

Develop and deliver program to build site-wide lean and six-sigma capabilities and learning program

Develop and execute site Learning roadmap to deliver future-ready capabilities, including digital fluency

Ensure plans are in place to deliver all required training (GxP & Non-GxP) via role-based curricula

Effectively partner with global learning leads and Quality to deliver required GSQ learning strategies

Monitor training KPIs monthly and work with SLT on action plans to address gaps.

Partners with global functions and BE community to implement applicable network initiatives

Align site initiatives with Quality and EHS to ensure regulatory and compliance requirements are fulfilled

Manage response to external productivity assessments (e.g. POBOS) and internal business audits (GIA)

Oversees site performance management process: monitors KPIs, identifies gaps, recommends actions

Facilitate site Crisis Management Team process & annual exercises to ensure leaders are trained

Manages the approved BE functional budget and resources

Minimum Requirements/Qualifications:

Minimum of 8+ years of experience in operational management roles, with a strong focus on GxP regulations, Operational Excellence, Continuous Improvement, or Lean Manufacturing.

Bachelor’s degree in relevant field (e.g. engineering, business) or equivalent work-experience

Advanced knowledge of lean management and problem-solving methodologies; Green Belt certification

Preferred

A master's degree (MBA, M.Sc.)

Experience with learning management systems in a regulated cGMP manufacturing environment

Experienced people leader, with proficiency in coaching

Knowledge of emerging digital technology, data analysis & manufacturing software (e.g., SAP, MES, etc.)

Project Management certification (e.g. PMP, sAFE, or similar).

Experience with strategy deployment/management.

Black Belt certification or equivalent.

Development during the role: Build advanced competencies on AOS during role.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location: USA - MA - Lexington - BIO OPS

U.S. Base Salary Range: $177,000.00 - $278,080.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

For information about our benefits, please click here .

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations USA - MA - Lexington - BIO OPS

Worker Type Employee

Worker Sub-Type Regular

Time Type Full time

Job Exempt Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.