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Tempus has filed one layoff notice in the last twelve months, covering 144 workers, most recently March 2026. These are public filings with state labor departments, and an open role can sit alongside them. See the filings

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About the job

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

We are looking for a commercially minded, strategic, and agile Director, HR Business Partner to lead strategy and execution for our Data & Applications (Data & Apps) business unit. In this high-impact leadership role, you will act as a core operating partner to the CEO of Data & Apps, as well as their executive leadership team and key cross-functional stakeholders.

You will operate as a business-first leader who leverages talent, structure, and organizational design to accelerate growth and commercial success. As the dedicated People Lead, you will manage a team of 2-3 HR Business Partners and take ownership of guiding and supporting the People strategy across the entire Data & Apps business unit.

Key Responsibilities

Executive Business Partnership: Serve as a trusted advisor and strategic thought partner, to the CEO of Data & Apps and their direct leadership team, aligning people strategies directly with commercial growth goals.

Business Unit Accountability: Take end-to-end accountability for the health, engagement, structure, and performance of the Data & Apps organization.

Team Leadership & Development: Lead, mentor, and coach a team of 2–3 HR Business Partners in a fluid, high-growth environment, helping to drive their professional growth and skill development.

Commercial & Strategic Alignment: Partner with leadership to help them translate commercial objectives (revenue targets, product launches, market expansion) into actionable workforce, talent, and organizational designs.

Agile Problem Solving: Approach business challenges with flexibility, creativity, good judgment, and speed while prioritizing pragmatic, outcome-driven solutions.

Organizational Design & Talent Strategy: Proactively evaluate team structures, workforce planning, succession management, and talent density to support growth and matrixed team dynamics.

Data-Driven Insights: Leverage people metrics and commercial data to identify trends, mitigate retention risks, and guide strategic decision-making across leadership.

Cross-Functional Integration: Partner closely with People Centers of Excellence—including Talent Acquisition, Compensation, Talent Development, Legal, and People Ops—to execute customized solutions tailored to Data & Apps.

Qualifications & Leadership Profile

Commercial & Business Acumen: Highly commercially minded with a track record of supporting revenue-generating, tech, or commercial teams (e.g., Sales, Product, GTM, or Business Units).

Agile & Solutions-Oriented Mindset: Proven ability to thrive in fast-paced, high-growth environments with ambiguous parameters, prioritizing business speed and flexibility while managing risk.

Pragmatic Partnering: A track record of acting as an agile business enabler rather than a policy administrator.

People Leadership Experience: Direct experience managing, developing, and inspiring a team of HR professionals or business partners.

Executive Presence & Influence: Exceptional communication, coaching, and stakeholder management skills with demonstrated success influencing C-suite and SVP/VP-level executives.

Experience: 10+ years of progressive HR/People experience, including significant experience as a strategic HRBP supporting business or tech organizations.

Education: Bachelor’s degree or equivalent practical experience required.

#LI-DA1

NYC: $165,000 - $220,000

The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.