Program Management Director/Sr. Director
BridgeBio Pharma
San Francisco, CA · $255k–$285k a year · Posted November 13, 2026
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About the job
Mavericks Wanted
When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.
Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.
What You'll Do
What You'll Do
The Director / Senior Director, Program Management, Portfolio Strategy & Management (PSM) runs the program review process that connects BridgeBio’s affiliate companies to executive decision-making. You will organize and plan the quarterly Program Review Meeting (PRM) cycle, help leadership and affiliates prepare, and track key deliverables and action items between meetings. You will also build and maintain the integrated timelines and milestone views behind the PRMs, and own the PSM Portal that gives leadership one trusted view of the portfolio. Senior Director scope includes broader program coverage, more complex cross-affiliate dependencies, and greater ownership of the PSM team’s structure and roadmap.
Responsibilities
Organize and plan the quarterly PRM cycle setting standards for planning, tracking and reporting
Support PRM governance and charter
Build and maintain integrated program timelines and milestone maps across affiliates, including cross-functional views that connect Regulatory, Clinical, CMC, Quality, Commercial and other functions
Identify risks, dependencies and resource conflicts across programs, including ex-US submission, approval and launch timing, and drive mitigation plans and escalation
Help prepare decision-ready materials for the Executive Team, the Board and functional heads, including portfolio decisions and development candidate nominations
Own the PSM Portal as product owner: set the roadmap, run beta and tiered-access launches, triage user feedback, and keep the dashboards (catalysts, competitive intelligence, program status) accurate and current
Manage the portal’s IT partnership, vendors and budget, including scoping statements of work and annual budget requests
Secure reliable, recurring data from groups outside PSM (affiliate teams, the International organization, portfolio strategy, IP and competitive intelligence)
Lead and develop the PMO capability
Build and improve program management dashboards, tools, templates and processes that scale as the company grows
Partner with Finance and Portfolio Strategy on long-range planning, budgets and resourcing
Capture decisions and follow-ups from each PRM and report progress against them at the next cycle
Where You'll Work
This role sits in the Office of the Chief Regulatory Officer (OCRO), and is part of the Portfolio Strategy & Management team. You will work daily with affiliate program teams, executive leadership and their chiefs of staff, IT, and the International organization.
Location: Hybrid, with 3 days a week in the SF/Palo Alto offices. Up to 10-20% travel may be required.
Who You Are
Director
8+ years in biotech or pharma; prior program or project management experience in drug development preferred
3+ years leading people or cross-functional teams
Senior Director (in addition)
12+ years in biotech or pharma, with 5+ years leading teams
Experience managing multiple late-stage programs or launches at the same time
Track record building program management processes and tools in a growing organization
Both levels
Solid understanding of cross-functional drug development (preclinical, CMC, regulatory, clinical, quality, commercial), global health authority guidelines and stage-gate decisions; submission and launch readiness experience a plus
Experience running governance for executive-level program reviews, including agendas, pre-reads, minutes and action tracking, and scheduling around senior executives
Experience owning an internal data product, portal or dashboard, including user adoption, access tiers, feedback and release planning; vendor and IT partnership experience a plus
Strong planning, risk management and cross-functional leadership skills, with the ability to prioritize complex and competing work across multiple programs at once
Proven ability to lead a matrixed team and influence without direct authority, including securing data and commitments from teams that do not report to you
Clear, concise communicator who builds strong relationships and can present compellingly to executives and the Board
Rare disease experience preferred; experience in a small to mid-sized biotech or a multi-affiliate structure valued
Expert in Microsoft Office (Excel, PowerPoint, Word, Outlook); experience with timeline management tools such as Smartsheet or MS Project
Master’s degree preferred; bachelor’s degree in a scientific, healthcare, life sciences or business field is fine. PMP or similar certification is a strong plus
What Success Looks Like
Program timelines and milestone maps leadership can rely on
Risks and dependencies surfaced early, with mitigation plans attached
A consistent, trusted view of program status in the PSM Portal, with broad adoption and data refreshed on an agreed quarterly cadence
Rewarding Those Who Make the Mission Possible
We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.
Financial Benefits
Market leading compensation
401K with 100% employer match on first 3% & 50% on the next 2%
Employee stock purchase program
Pre-tax commuter benefits
Referral program with $2,500 award for hired referrals
Health & Wellbeing
Comprehensive health care with 100% premiums covered, at no cost to you and dependents
Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
Hybrid work model: employees have the autonomy in where and how they do their work
Unlimited flexible paid time off
Paid parental leave: 4 months for birthing parents & 2 months for non-birthing parents
Flex spending accounts & company-provided group term life & disability
Subsidized lunch via Forkable on days worked from our office
Skill Development & Career Paths
People are part of our growth and success story: from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
Career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching
Strong performance is celebrated with financial rewards, peer-to-peer recognition and growth opportunities
At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states. Salary : [$X - $Y USD, to be confirmed with Total Rewards]
At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.
Salary $255,000 — $285,000 USD
As a global company, our comprehensive benefits may vary based on location. We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.
For BridgeBio Full-Time U.S Based Roles:
Financial & Rewards
Market-leading compensation
401(k) with employer match
Employee Stock Purchase Program (ESPP)
Pre-tax commuter benefits (transit and parking)
Referral bonus for hired candidates
Subsidized lunch and parking on in-office days
Health & Well-Being
100% employer-paid medical, dental, and vision premiums for you and your dependents
Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)
Fertility & family-forming benefits
Expanded mental health support (therapy and coaching resources)
Hybrid work model with flexibility
Flexible, “take-what-you-need” paid time off and company-paid holidays
Comprehensive paid medical and parental leave to care for yourself and your family
Skill Development & Career Paths:
People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching
We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities
By applying, you acknowledge that BridgeBio will process your personal information as described in our Global Candidate Privacy Notice .