NextChapter

Principal Applied Scientist jobs: 40 open roles

Open principal applied scientist jobs taken from employers’ own career sites and checked to still be open.

Question 1

Where are you right now?

Why we ask: a laid-off week and a thinking-about-a-move week look nothing alike. No résumé, no account.

Get new principal applied scientist jobs by email

We’ll email you when new matches are posted. No account needed.

The market for principal applied scientist work

Every figure names its source. Skills and AI-skill shares describe the whole Research function this title sits in.

Verified open principal applied scientist jobs
40

Source: NextChapter, checked against employer career sites, last 7 days.

See the detail →
Research openings that ask for AI skills
13%

Source: NextChapter verified openings.

Research openings that are remote
4%

Source: NextChapter verified openings.

See the detail →

Skills most often named in openings

  1. 1. python13%
  2. 2. machine learning11%
  3. 3. onboarding8%
  4. 4. excel7%
  5. 5. project management6%
  6. 6. c++6%
  7. 7. java4%
  8. 8. powerpoint3%

AI skills worth building for this work

  1. 1. AI tools in daily work
  2. 2. Gen-AI assistants (ChatGPT, Copilot, Claude)
  3. 3. Prompt design
  4. 4. AI coding assistants
  5. 5. AI workflow automation
  6. 6. Automation platforms (Zapier, n8n, Power Automate)

More on Research roles

Where principal applied scientist experience can go next

Career moves the skills carry over to, closest fit first. Time is how long a move usually takes.

  • Data science and machine learning

    Close fit · A few months

    Data science is the most common move out of the lab: same scientific method, applied to business data.

    Carries over: Statistics, Experiment design, Programming for analysis

  • Compliance and risk

    Close fit · A few months

    Regulatory affairs and quality roles at pharma, biotech and manufacturing companies want scientists.

    Carries over: Regulatory knowledge, Documentation, Quality systems

  • Clinical operations and care coordination

    Adjacent · A few months

    Clinical research and study management roles build on lab and research experience.

    Carries over: Research protocols, Data integrity, Study management

  • Solutions consulting and sales engineering

    Adjacent · A few months

    Application scientist and technical sales roles pay more for scientists who like people.

    Carries over: Deep technical knowledge, Explaining science simply, Solving customer problems

How would your résumé fare for principal applied scientist?

Paste it to see which skills these openings ask for and which your résumé leaves out. It runs here in your browser, so nothing you paste is sent.

Paste at least a few lines to check it.

Make it yours

Tell us your state and where to reach you. Attach your résumé if you want a real read on it.

Open principal applied scientist jobs

Verified against the employer’s own career site within the last week.

Showing the newest 15 of about 40 verified open jobs here. Search all jobs

Search all principal applied scientist jobs

Where principal applied scientist jobs are

Principal Applied Scientist jobs by city and state

Employers hiring principal applied scientists

  • Amazon 24
  • Microsoft 4
  • Swiftkey 4
  • Oracle 3
  • Opower 3
  • AWS 1
  • UiPath 1

Related job titles

Hiring principal applied scientist roles?

Leave your work email. We'll send how to reach people searching for principal applied scientist jobs.

See employer options

Do you want this for your own search?

A free account turns this page into your plan: a plain-language read on principal applied scientist, jobs matched to you and a weekly action plan.

Yes, start free