Senior Director, Total Rewards and HRIS
Vir Biotechnology
San Francisco, CA · Posted October 1, 2026
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About the job
Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN ® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.
Vir Biotechnology has exclusive rights to the universal PRO-XTEN ® masking platform for oncology and infectious disease. PRO-XTEN ® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.
We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.
THE OPPORTUNITY
Reporting to the CHRO, the Sr Director of Total Rewards and HRIS will lead the design, delivery, and governance of Vir Bio's global compensation and benefits programs. You will also be responsible for the strategy and implementation of HR analytics initiatives and HRIS oversight across the HR function and broader organization.
In this role you will partner with senior business leaders and the HR leadership team to translate business strategy into total rewards strategies that attract, reward, and retain key talent. You will ensure programs are competitive, equitable, and aligned with organizational objectives.
The ideal candidate will be a hands-on leader with deep compensation and benefits expertise, strong analytical capabilities, and a track record of developing successful strategies. This position requires the ability to balance strategic thinking with tactical execution-conceptualizing innovative solutions while driving day-to-day program administration and continuous improvement.
This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.
WHAT YOU'LL DO
Lead the strategic design, implementation, and administration of global compensation and benefits programs, including base pay structures, short-term and long-term incentive plans (including commercial sales incentive plans), recurring compensation cycles, and program targets
Design and implement benefits programs through needs analysis, competitive benchmarking, and cost-effectiveness evaluation
Manage annual benefit enrollment, plan changes, wellness initiatives, and compensation planning cycles
Conduct competitive market analysis to ensure programs remain competitive, equitable, and aligned with business objectives
Ensure compliance with federal, state, and international compensation and benefits regulations
Serve as the hands-on lead for executive compensation, including program design and benchmarking
Prepare and present analyses and recommendations to senior leadership, the Board of Directors, and the Compensation Committee
Strategically lead all aspects of management and coordination with the Compensation Committee including meeting planning, deliverable preparation, meeting facilitation, and tracking of follow up actions.
Align compensation programs with performance management processes to drive accountability and reward performance
Oversee global mobility programs including immigration and relocation
Develop and implement HR analytics strategy and provide HRIS oversight to ensure data integrity
Execute total rewards communication strategies to ensure employees understand and value their compensation and benefits
Manage a high-performing team across compensation, benefits, and analytics functions
WHO YOU ARE AND WHAT YOU BRING
BA/BS and 12+ years or MS/MBA and 10+ years of relevant experience preferred
Proven track record leading compensation and benefits teams at a public company
Experience within a commercial-stage life sciences organization is strongly preferred
Deep expertise in executive compensation programs, including presenting to Board of Directors, Compensation Committees, and external stakeholders
Comprehensive knowledge of compensation regulatory, compliance, and legislative requirements
Strong analytical capabilities with experience performing complex reporting and analysis
Superior executive presence and communication skills with ability to present credibly at all organizational levels
Proven ability to build trust with stakeholders through strong organizational skills and proactive problem-solving
Experience with HRIS systems, including UKG
Strong people management skills with a track record of developing high-performing teams
Experience managing vendor relationships with benefits brokers, consultants, and external partners
Collaborative leadership style with a hands-on approach to problem-solving and stakeholder engagement
#LI-AS1
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WHO WE ARE AND WHAT WE OFFER
The expected salary range for this position is $227,500 to $318,000 per year. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.
Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications. All full-time employees receive a package that includes compensation, bonus and equity as well as many other Vir Biotechnology benefits and perks such as health and welfare benefit plans, non-accrual paid time off, company shut down for holidays, commuter benefits, 401K match and lunch each day in the office.
Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.
All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics.
This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment.
Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.
For hires based in the United States, Vir Biotechnology, participates in E-Verify .
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