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HR Lead

Faeth Therapeutics

Remote · San Francisco, CA · Posted October 27, 2026

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About the job

Faeth Therapeutics is a clinical-stage oncology company listed on Nasdaq that recently raised $200M in funding. With a strong scientific foundation and a founding team that includes the discoverer of our target pathway, we are advancing PIKTOR, a multi-node PI3K/AKT/mTOR inhibitor program, toward multiple near-term milestones. We are a small, focused team where every person has direct impact — united by a shared commitment to care deeply, create boldly, and never stop learning.

The HR Lead will own all aspects of Human Resources, People Operations, Compensation, Benefits, Compliance, and Employee Relations,. This role is ideal for a proactive HR professional who thrives in a fast-paced biotech environment and enjoys building scalable processes while serving as a trusted advisor to employees and leadership.

Reports to: Chief of Staff

Location: Remote (U.S.)

Responsibilities:

Lead all onboarding and offboarding processes to ensure a seamless employee experience.

Serve as the primary point of contact for employee questions and support.

Manage compensation planning, benchmarking, and market analyses.

Own equity administration and equity planning processes.

Manage annual compensation review cycles and salary adjustments.

Administer employee benefits programs and manage vendor relationships.

Manage and oversee the company’s 401(k) program, including establishment and administration of a 401(k) committee.

Serve as system administrator for HRIS platforms and related people systems.

Manage payroll preparation and coordinate with payroll providers.

Maintain accurate employee records and HR data and ensure compliance with federal, state, and local employment regulations.

Oversee leave administration, including parental, medical, and other protected leaves.

Lead and administer the annual performance review process.

Lead learning and development programs that support employee growth and leadership development.

Lead company-wide communications and employee engagement activities.

Organize and facilitate All Hands meetings, team lunches, happy hours, and company events.

Requirements:

Bachelor's degree in Human Resources, Business Administration, or related field.

5+ years of progressive HR experience in biotechnology, pharmaceutical, or life sciences organizations.

Strong knowledge of employment law, HR compliance, benefits administration, and employee relations.

Experience managing compensation programs, benchmarking, and equity administration.

Experience administering HRIS systems and payroll processes.

Demonstrated ability to manage sensitive and confidential information with discretion.

Excellent interpersonal, communication, and relationship-building skills.

Strong project management and organizational abilities.

Ability to operate effectively in a high-growth, entrepreneurial environment.

Preferred:

Experience supporting venture-backed or high-growth biotech companies.

Experience with Radford compensation surveys and benchmarking.

Experience working with Boards of Directors and Compensation Committees.

SHRM-CP, SHRM-SCP, PHR, or SPHR certification.

Experience managing immigration processes and employment-related legal matters.

Compensation Range: $130,000 - $160,000 (actual compensation may vary based on experience, qualifications and location)

Working at Faeth

Benefits:

Competitive salary and equity in a well-funded, clinical-stage biotech

100% remote work and flexible schedule

Health, dental, and vision for you and your dependents

Flexible time off

Generous parental leave

Traditional and Roth 401k

Mission oriented, remote first culture

We are an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

All offers of employment are contingent upon satisfactory completion of a background check and verification of eligibility to work in the United States.