Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!

The Director, Market Research, Competitive Intelligence & Forecasting will lead the development of market insights, competitive intelligence, and commercial forecasts that inform Definium Therapeutics’ commercial strategy, portfolio planning, launch readiness, and long range business planning. The individual will own the integrated process for understanding the market, anticipating competitive change, and translating evidence into patient-based demand and revenue forecasts. This role will partner closely with Finance, Marketing, Market Access, Medical Affairs, Clinical Development, and senior leadership and will manage the functional budget and external partners for market research, competitive intelligence, and forecasting.

Responsibilities:

Own the integrated market research, competitive intelligence, and forecasting strategy for assigned assets and indications

Develop and execute primary market research across healthcare professionals, patients, caregivers, payers, and health systems to address priority business questions

Integrate primary research with epidemiology, claims, electronic health record, prescription, payer, and other secondary data to generate actionable insights

Lead competitive intelligence monitoring and assess clinical, regulatory, scientific, access, and commercial developments that may affect strategy or market opportunity

Own patient-based demand and revenue forecasts, including transparent assumptions, data sources, model documentation, and governance

Lead Long-Range Planning, budget, Latest Estimate, and forecast-update cycles in partnership with Finance and Commercial leadership

Develop base, upside, downside, and strategic scenarios, with sensitivity analyses that quantify key risks, opportunities, and forecast drivers

Translate research and competitive developments into implications for market assumptions, launch strategy, portfolio decisions, and investment priorities

Communicate insights, forecast outputs, risks, opportunities, and recommendations through concise, executive-ready materials for senior leadership and the Board

Manage market research agencies, forecasting consultants, competitive intelligence partners, data providers, functional budgets, and internal knowledge repositories

Qualifications:

Required:

Bachelor’s degree in business, life sciences, economics, analytics, statistics, public health, marketing, or a related discipline.

Minimum 8 years of progressive pharmaceutical or biotechnology experience across market research, competitive intelligence, forecasting, commercial analytics, business insights, or related disciplines

Demonstrated experience independently developing or managing pharmaceutical patient-based demand and/or revenue forecasts

Experience with Long-Range Planning, annual budget, Latest Estimate, forecast updates, scenario modeling, and sensitivity analysis

Demonstrated experience designing and executing primary market research and integrating findings with secondary data and quantitative analytics

Strong understanding of the U.S. pharmaceutical commercialization process and healthcare environment

Experience with claims, electronic health records, prescription data, epidemiology, payer/access data, and competitive intelligence sources

Experience managing external vendors, projects, and functional budgets

Ability to travel up to 10% by air and/or car, including occasional overnight travel

Preferred:

Advanced degree in business, life sciences, economics, analytics, public health, or a related field

Experience in psychiatry, neuroscience, specialty therapeutics, or another complex specialty market

Experience forecasting a pre-launch asset through commercialization, including launch uptake and longer-term demand scenarios

Experience supporting product launch, indication expansion, lifecycle strategy, or portfolio evaluation

Experience integrating primary research, epidemiology, claims, competitive intelligence, analogs, and financial assumptions into commercial forecasts

Experience establishing or evolving a market insights, competitive intelligence, and/or forecasting capability within a small or mid-sized biotechnology company

Experience presenting market insights and forecasts to senior leadership or executive decision-making forums

Familiarity with modern forecasting, analytics, visualization, and AI-enabled insight tools

Individual compensation within the range is determined based on factors such as relevant skills, experience, qualifications, scope of the role, and other legitimate business considerations. In addition to base salary, this role may be eligible for bonus and equity opportunities. We also offer a comprehensive benefits package including health insurance, 401(k) with company match, flexible time off and additional wellness benefits and perks. Learn more about our benefits on our Careers page.

The anticipated base salary range for this position is: $195,000 — $290,000 USD