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Chief Clinical Innovation Officer

Ascension Seton

Remote · St Louis, MO · Posted November 3, 2026

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About the job

Location: Remote with travel

Salary: $313,891 - $431,600 annual. The expected compensation range for this position is from the minimum to the midpoint of the pay grade. Actual compensation will be based on factors such as experience, education, and organizational fit. This position is eligible for participation in the annual bonus program.

The Chief Clinical Innovation Officer provides strategic leadership in the design, development, implementation, and optimization of clinical practices across the organization. This role advances clinical transformation by establishing evidence-based care standards, enabling technology-integrated clinical workflows, and driving sustainable changes in care delivery to improve quality, safety, health outcomes, and patient and clinician experiences.

Working in close partnership with enterprise, market, and clinical leadership, this executive translates organizational clinical priorities into scalable strategies and operational solutions. The Vice President champions clinical innovation, accelerates adoption of technology-enabled care models, and drives measurable improvements aligned with the quadruple aim and Ascension's mission.

Clinical Strategy & Transformation: Develops and advances enterprise clinical practice strategies that align with organizational priorities, improve care delivery, and drive measurable improvements in quality, safety, clinical outcomes, and patient and clinician experiences.

Clinical Practice Optimization: Partners with clinical leaders, physicians, clinicians, and operational stakeholders to establish, standardize, and optimize evidence-based clinical practices, care standards, and workflows across the organization.

Technology-Enabled Care Delivery: Collaborates with Ascension Technologies, Studio leadership, and clinical and operational partners to evaluate, implement, and optimize technology-enabled solutions that advance clinical practice, improve workflow efficiency, and support high-reliability healthcare delivery.

Virtual Care Innovation: Partners with virtual care leadership to develop and operationalize innovative care models, clinical use cases, and workflows that expand access, enhance care coordination, and improve the delivery of care.

Change Leadership & Adoption: Leads enterprise alignment, stakeholder engagement, and change management strategies to drive adoption and sustained integration of clinical practice improvements across diverse clinical environments.

Clinical Experience & Workforce Effectiveness: Identifies barriers and emerging opportunities affecting clinical practice and develops strategies that improve care team effectiveness, reduce operational friction, and enhance the clinician experience.

Performance & Outcomes Management: Establishes performance measures, monitors key clinical and operational indicators, and evaluates the effectiveness of clinical redesign initiatives to ensure measurable, sustainable outcomes.

Executive Partnership & Influence: Advises and collaborates with senior enterprise, market, and clinical leaders to translate strategic priorities into actionable clinical initiatives and advance organizational performance.

Financial & Resource Stewardship: Partners in the development and oversight of operating budgets, financial targets, workforce plans, and resources necessary to execute clinical practice strategies.

Execution & Accountability: Establishes short- and long-term objectives, monitors progress against strategic plans and budgets, and ensures initiatives deliver intended clinical, operational, and financial results.

Licensure / Certification / Registration

Required Credential(s): Physician MD/DO obtained prior to hire date or job transfer date.

Education

Associate's degree/Bachelor's degree with 7 years of applicable cumulative job specific experience required, with 4 of those years being in leadership/management.

Additional Preferences:

Graduate of an accredited medical school.

Additional graduate-level education in healthcare administration, business administration, public health, or a related discipline preferred.

Significant progressive clinical and physician leadership experience within a complex healthcare environment.

Demonstrated experience leading clinical transformation, practice redesign, and enterprise-wide improvement initiatives.

Experience developing and implementing technology-enabled clinical workflows and innovative care delivery models.

Demonstrated ability to influence senior executives, physicians, clinical leaders, and operational stakeholders across a matrixed organization.

Experience driving measurable improvements in clinical quality, patient safety, operational performance, and clinician experience.

Demonstrated financial acumen and experience managing budgets, resources, and performance outcomes.

Ascension is a leading nonprofit Catholic health system with a culture and associate experience grounded in service, growth, care and connection. We empower our 99,000+ associates to bring their skills and expertise every day to reimagining healthcare, together. Recognized as one of the Best 150+ Places to Work in Healthcare and a Military-Friendly Gold Employer, you'll find an inclusive and supportive environment where your contributions truly matter.

Equal employment opportunity employer

Ascension provides Equal Employment Opportunities (EEO) to all associates and applicants for employment without regard to race, color, religion, sex/gender, sexual orientation, gender identity or expression, pregnancy, childbirth, and related medical conditions, lactation, breastfeeding, national origin, citizenship, age, disability, genetic information, veteran status, marital status, all as defined by applicable law, and any other legally protected status or characteristic in accordance with applicable federal, state and local laws. For further information, view the EEO Know Your Rights (English) poster or EEO Know Your Rights (Spanish) poster.

Fraud prevention notice

Prospective applicants should be vigilant against fraudulent job offers and interview requests. Scammers may use sophisticated tactics to impersonate Ascension employees. To ensure your safety, please remember: Ascension will never ask for payment or to provide banking or financial information as part of the job application or hiring process, our legitimate email communications will always come from an @ascension.org email address; do not trust other domains, and an official offer will only be extended to candidates who have completed a job application through our authorized applicant tracking system.

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